Evidence map›Paper›PMID 28978639›Full record

ArticleThe Journal of experimental biology2017

Molecular plasticity and functional enhancements of leg muscles in response to hypergravity in the fruit fly

Rudolf J Schilder, Megan Raynor

Open access · greenAbstract read
In one paragraph

Article in The Journal of experimental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rudolf J SchilderDepartment of Entomology, Pennsylvania State University, 501 Ag Sciences & Industries Building, University Park, PA 16802, USA rjs360@psu.edu.ORCID 0000-0003-1229-1274
Megan RaynorDepartment of Biology, Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA.
Pennsylvania State University · US

Funding

Macronutrient Regulation of Alternative Pre-mRNA SplicingR01DK094141 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KIMBALL, SCOT R · 2013 to 2016
$1.3M
NIDDK NIH HHS R01 DK094141
6 · The paper itself

Abstract

Studies of organismal and tissue biomechanics have clearly demonstrated that musculoskeletal design is strongly dependent on experienced loads, which can vary in the short term, as a result of growth during life history and during the evolution of animal body size. However, how animals actually perceive and make adjustments to their load-bearing musculoskeletal elements that accommodate variation in their body weight is poorly understood. We developed an experimental model system that can be used to start addressing these open questions, and uses hypergravity centrifugation to experimentally manipulate the loads experienced by

Indexed as

HypergravityAlternative SplicingAnimalsBody WeightDrosophila melanogasterExtremitiesInsect ProteinsMaleMuscle, SkeletalTroponin TInsect ProteinsTroponin TAlternative splicingBody massBody weightCentrifugationMuscle performanceMusculoskeletalTroponin TWeight sensing

Identifiers

PMID28978639
PMCPMC5665435
OpenAlexW2761433878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.