Evidence map›Paper›PMID 28978473›Full record

ArticleCell reports2017

Generation of RORγt

Byung-Seok Kim, Huiping Lu, Kenji Ichiyama, Xiang Chen, Yi-Bing Zhang, Nipun A Mistry, Kentaro Tanaka, Young-Hee Lee, Roza Nurieva, Li Zhang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 129 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
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  6. Article
  7. Article
  8. Review
  9. The emerging role of T cells in depression.Frontiers in psychiatry · 2026
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Lupus susceptibility geneScience advances · 2024
    Article
  20. Review

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Byung-Seok KimDepartment of Immunology, MD Anderson Cancer Center, Houston, TX 77054, USA; Laboratory of Immune Regulation, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Huiping LuInstitute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China.
Kenji IchiyamaDepartment of Immunology, MD Anderson Cancer Center, Houston, TX 77054, USA.
Xiang ChenDepartment of Immunology, MD Anderson Cancer Center, Houston, TX 77054, USA.
Yi-Bing ZhangState Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.
Nipun A MistryDepartment of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, TX 77054, USA.
Kentaro TanakaDepartment of Immunology, MD Anderson Cancer Center, Houston, TX 77054, USA.
Young-Hee LeeDepartment of Immunology, MD Anderson Cancer Center, Houston, TX 77054, USA.
Roza NurievaDepartment of Immunology, MD Anderson Cancer Center, Houston, TX 77054, USA.
Li ZhangDepartment of Environmental Health, University of Cincinnati, Cincinnati, OH 45219, USA.
Xuexian YangDepartment of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM 87131, USA.
Yeonseok ChungLaboratory of Immune Regulation, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Wei JinInstitute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China.
Seon Hee ChangDepartment of Immunology, MD Anderson Cancer Center, Houston, TX 77054, USA. Electronic address: shchang@mdanderson.org.
Chen DongInstitute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China. Electronic address: chendong@tsinghua.edu.cn.
The University of Texas MD Anderson Cancer Center · USTsinghua University · CNSeoul National University · KRInstitute of Hydrobiology · CNUniversity of Cincinnati · USUniversity of New Mexico · US

Funding

Transcriptional regulation of inflammatory helper T Cell differentiationR01AR050772 · NIAMS · UNIVERSITY OF WASHINGTON · PI DONG, CHEN · 2003 to 2016
$4.5M
NIAMS NIH HHS R01 AR050772
6 · The paper itself

Abstract

Th17 cells are potent mediators in autoimmune diseases, and RORγt is required for their development. Recent studies have shown that RORγt

Indexed as

Adoptive TransferAnimalsAutoimmunityCell DifferentiationEncephalomyelitis, Autoimmune, ExperimentalForkhead Transcription FactorsGene Expression RegulationGenes, ReporterGreen Fluorescent ProteinsInducible T-Cell Co-Stimulator ProteinInterleukin-6MiceMice, Inbred BALB CMice, Inbred C57BLMice, TransgenicMyelin-Oligodendrocyte GlycoproteinCCR6 protein, mouseForkhead Transcription FactorsFoxp3 protein, mouseGreen Fluorescent ProteinsIcos protein, mouseInducible T-Cell Co-Stimulator ProteinInterleukin-6interleukin-6, mouseMyelin-Oligodendrocyte Glycoproteinmyelin oligodendrocyte glycoprotein (35-55)Nuclear Receptor Subfamily 1, Group F, Member 3Peptide FragmentsReceptors, CCR6Stat3 protein, mouseSTAT3 Transcription FactorautoimmunityFoxp3IL-17RORγtTr17Treg

Identifiers

PMID28978473
PMCPMC5716359
OpenAlexW2762184317

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.