ArticleBiophysical journal2017
Determination of Cell Membrane Capacitance and Conductance via Optically Induced Electrokinetics.
Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Machine Learning-Based Detection ofPathogens (Basel, Switzerland) · 2026Article
- Optoelectronic Tweezers for Single-Cell Research: Principles, Applications, and Prospects.Cyborg and bionic systems (Washington, D.C.) · 2026Review
- Dielectrophoresis and ζ-potential as potential low-cost complements to patch clamp for measurement of cell electrophysiology.PloS one · 2026Article
- Microfluidic Electroporation Arrays for Investigating Electroporation-Induced Cellular Rupture Dynamics.Biosensors · 2024Article
- Early differentiation of mesenchymal stem cells is reflected in their dielectrophoretic behavior.Scientific reports · 2024Article
- HectoSTAR μLED Optoelectrodes for Large-Scale, High-Precision In Vivo Opto-Electrophysiology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Accurate and Automatic Extraction of Cell Self-Rotation Speed in an ODEP Field Using an Area Change Algorithm.Micromachines · 2022Article
- Isolation method ofBiomedical optics express · 2022Article
- A physical perspective to understand myelin. I. A physical answer to Peter's quadrant mystery.Frontiers in neuroscience · 2022Article
- Dielectrophoresis as a Tool to Reveal the Potential Role of Ion Channels and Early Electrophysiological Changes in Osteoarthritis.Micromachines · 2021Article
- Development of New Strategies Using Extracellular Vesicles Loaded with Exogenous Nucleic Acid.Pharmaceutics · 2020Review
- Determination of Dielectric Properties of Cells using AC Electrokinetic-based Microfluidic Platform: A Review of Recent Advances.Micromachines · 2020Review
- Detection of Rare Objects by Flow Cytometry: Imaging, Cell Sorting, and Deep Learning Approaches.International journal of molecular sciences · 2020Review
- Simultaneously Quantifying Both Young's Modulus and Specific Membrane Capacitance of Bladder Cancer Cells with Different Metastatic Potential.Micromachines · 2020Article
- A Review on Optoelectrokinetics-Based Manipulation and Fabrication of Micro/Nanomaterials.Micromachines · 2020Review
- New insights into anhydrobiosis using cellular dielectrophoresis-based characterization.Biomicrofluidics · 2019Article
- Optoelectrokinetics-based microfluidic platform for bioapplications: A review of recent advances.Biomicrofluidics · 2019Review
- Bioelectrical control of positional information in development and regeneration: A review of conceptual and computational advances.Progress in biophysics and molecular biology · 2018Review
- Determination of the Three-Dimensional Rate of Cancer Cell Rotation in an Optically-Induced Electrokinetics Chip Using an Optical Flow Algorithm.Micromachines · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell membrane capacitance and conductance are key pieces of intrinsic information correlated with the cellular dielectric parameters and morphology of the plasma membrane; these parameters have been used as electrophysiological biomarkers to characterize cellular phenotype and state, and they have many associated clinical applications. Here, we present our work on the non-invasive determination of cell membrane capacitance and conductance by an optically activated microfluidics chip. The model for determining the cell membrane capacitance and conductance was established by a single layer of the shell-core polarization model. Three-dimensional finite-element analyses of the positive and negative optically induced dielectrophoresis forces generated by the projected light arrays of spots were performed, thus providing a theoretical validation of the feasibility of this approach. Then, the crossover frequency spectra for four typical types of cells (Raji cells, MCF-7 cells, HEK293 cells, and K562 cells) were experimentally investigated by using a micro-vision based motion-tracking technique. The different responses of these cells to the positive and negative ODEP forces were studied under four different liquid conductivities by automatic observation and tracking of the cellular trajectory and texture during the cells' translation. The cell membrane capacitance and conductance were determined from the curve-fitted spectra, which were 11.1 ± 0.9 mF/m
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.