Evidence map›Paper›PMID 28978306›Full record

Trial reportBMC cancer2017

Respiratory-gated (4D) contrast-enhanced FDG PET-CT for radiotherapy planning of lower oesophageal carcinoma: feasibility and impact on planning target volume.

Andrew Scarsbrook, Gillian Ward, Patrick Murray, Rebecca Goody, Karen Marshall, Garry McDermott, Robin Prestwich, Ganesh Radhakrishna

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02285660 (Evaluation of 4D-contrast Enhanced PET-CT in Tumour Volume Definition for Patients With Lung, Lower Oesophageal and Pancreatic Carcinomas.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02285660 naunknown statusnot on this map

Evaluation of 4D-contrast Enhanced PET-CT in Tumour Volume Definition for Patients With Lung, Lower Oesophageal and Pancreatic Carcinomas.

TypeinterventionalSponsorThe Leeds Teaching Hospitals NHS TrustRan2011 to 2014ConditionsLung Carcinoma, Lower Oesophageal Carcinoma, Pancreatic CarcinomaArms4D PET-CT Scan, No intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Motion-compensated FDG PET/CT for oesophageal cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrew ScarsbrookDepartment of Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK. a.scarsbrook@nhs.net.ORCID http://orcid.org/0000-0002-4243-032X
Gillian WardDepartment of Medical Physics and Engineering, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Patrick MurrayDepartment of Clinical Oncology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Rebecca GoodyDepartment of Clinical Oncology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Karen MarshallDepartment of Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Garry McDermottDepartment of Nuclear Medicine, Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Level 1, Bexley Wing, Beckett Street, Leeds, LS9 7TF, UK.
Robin PrestwichDepartment of Clinical Oncology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Ganesh RadhakrishnaThe Christie Hospital, Wilmslow Road, Manchester, M20 4 BX, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the feasibility and potential impact on target delineation of respiratory-gated (4D) contrast-enhanced

methodsFifteen patients were recruited into the study. Imaging included 4D PET-CT, 3D PET-CT, endoscopic ultrasound and planning 4D CT. Target volume delineation was performed on 4D CT, 4D CT with co-registered 3D PET and 4D PET-CT. Planning target volumes (PTV) generated with 4D CT (PTV

resultsMean PTV

conclusionsPlanning 4D PET-CT is feasible with careful patient selection. PTV generated using 4D CT, 3D PET-CT and 4D PET-CT were of similar volume, however, overlap analysis demonstrated that approximately 20% of PTV

trial registrationClinicalTrials.gov Identifier - NCT02285660 (Registered 21/10/2014).

Indexed as

Radiotherapy Planning, Computer-AssistedAdolescentAdultAgedAged, 80 and overCarcinomaEsophageal NeoplasmsFemaleFluorodeoxyglucose F18Four-Dimensional Computed TomographyHumansMaleMiddle AgedPositron Emission Tomography Computed TomographyRadiotherapy DosageRespiratory-Gated Imaging TechniquesFluorodeoxyglucose F18FDG pet-CtFour-dimensional CTOesophageal carcinomaRadiotherapy treatment planningTarget volume definition

Identifiers

PMID28978306
PMCPMC5628433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.