Evidence map›Paper›PMID 28978282›Full record

ArticleTissue engineering. Part C, Methods2018

Acute Swine Model for Assessing Biocompatibility of Biomedical Interface Materials.

Tohru Takaseya, Hideyuki Fumoto, Junmin Zhu, Akira Shiose, Mariko Kobayashi, Masako Fujiki, Yoko Arakawa, Raymond Dessoffy, Larry D Kramer, Kiyotaka Fukamachi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering. Part C, Methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tohru Takaseya1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Hideyuki Fumoto1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Junmin Zhu2 Chemical Abstracts Service , Columbus, Ohio.
Akira Shiose1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Mariko Kobayashi1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Masako Fujiki1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Yoko Arakawa1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Raymond Dessoffy1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Larry D Kramer1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.
Kiyotaka Fukamachi1 Department of Biomedical Engineering, Lerner Research Institute , Cleveland Clinic, Cleveland, Ohio.

Funding

NEW BIOMEDICAL INTERFACE MATERIALSR01EB002067 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI MARCHANT, ROGER E · 2003 to 2007
$1.6M
NIBIB NIH HHS R01 EB002067
6 · The paper itself

Abstract

We established an acute animal model for early, straightforward, and reproducible assessment of a biocompatible material interface. Bilateral femoral artery-to-vein shunts were created in 12 pigs: two tubes per shunt, the left two coated and the right two uncoated. We evaluated two groups: uncontrolled flow (UF; shunt flow unregulated) and controlled flow (CF; shunt flow ∼50 mL/min). For each case on each side, two shunts were evaluated: one for 1 h and the other for 3 h. Arterial blood gas and complete blood count were recorded at baseline, 1, and 3 h. Mean shunt flows were 532 ± 88 mL/min UF and 52 ± 8 mL/min CF. Differences in flow were much smaller in CF (0.5 mL/min; 1% of mean flow) than UF (24.8 mL/min; 5% of mean flow). In UF, significant changes occurred: in pH, from start of shunting through 1 h; in pO

Indexed as

Models, AnimalAnimalsBiocompatible MaterialsBlood Flow VelocityFemoral ArteryFemoral VeinHemodynamicsMaleSwineBiocompatible Materialsarteriovenous shuntbiocompatible materialsblood coagulationdevice coatingswine model

Identifiers

PMID28978282
PMCPMC5816348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.