Evidence map›Paper›PMID 28978267›Full record

ReviewTissue engineering. Part B, Reviews2018

Review of Vascular Graft Studies in Large Animal Models.

Rui Han Liu, Chin Siang Ong, Takuma Fukunishi, Kingsfield Ong, Narutoshi Hibino

Abstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 81 citations in OpenAlex.

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  9. Hemodynamics and Wall Mechanics of Vascular Graft Failure.Arteriosclerosis, thrombosis, and vascular biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Rui Han Liu1 Division of Cardiac Surgery, The Johns Hopkins Hospital , Baltimore, Maryland.
Chin Siang Ong1 Division of Cardiac Surgery, The Johns Hopkins Hospital , Baltimore, Maryland.
Takuma Fukunishi1 Division of Cardiac Surgery, The Johns Hopkins Hospital , Baltimore, Maryland.
Kingsfield Ong2 Department of Cardiac, Thoracic and Vascular Surgery, National University Health System , Singapore, Singapore .
Narutoshi Hibino1 Division of Cardiac Surgery, The Johns Hopkins Hospital , Baltimore, Maryland.
Johns Hopkins Hospital · USNational University Health System · SG

Funding

Training Program in Cellular and Molecular MedicineT32GM008752 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI RAO, RAJINI · 2000 to 2019
$11.7M
NIGMS NIH HHS T32 GM008752
6 · The paper itself

Abstract

As the incidence of cardiovascular disease continues to climb worldwide, there is a corresponding increase in demand for surgical interventions involving vascular grafts. The current gold standard for vascular grafts is autologous vessels, an option often excluded due to disease circumstances. As a result, many patients must resort to prosthetic options. While widely available, prosthetic grafts have been demonstrated to have inferior patency rates compared with autologous grafts due to inflammation and thrombosis. In an attempt to overcome these limitations, many different materials for constructing vascular grafts, from modified synthetic nondegradable polymers to biodegradable polymers, have been explored, many of which have entered the translational stage of research. This article reviews these materials in the context of large animal models, providing an outlook on the preclinical potential of novel biomaterials as well as the future direction of vascular graft research.

Indexed as

Blood Vessel ProsthesisModels, CardiovascularAnimalsAutograftsBiocompatible MaterialsBlood VesselsHumansInflammationThrombosisVascular Surgical ProceduresBiocompatible Materialsbiomaterialslarge animal modelstissue-engineered vascular graftsvascular grafts

Identifiers

PMID28978267
PMCPMC6426275
OpenAlexW2762924193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.