Evidence map›Paper›PMID 28978149›Full record

ArticleOncotarget2017

The long non-coding RNA NONHSAT062994 inhibits colorectal cancer by inactivating Akt signaling.

Xiao-Shun He, Ling-Chuan Guo, Ming-Zhan Du, Shan Huang, Ren-Peng Huang, Sheng-Hua Zhan, Dong-Mei Gu, Wei-Shuo Liu, Xi-Ming Wang, Hua Wu and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xiao-Shun He *Department of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Ling-Chuan Guo *Department of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Ming-Zhan Du *Department of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Shan HuangDepartment of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Ren-Peng HuangDepartment of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Sheng-Hua ZhanDepartment of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Dong-Mei GuDepartment of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Wei-Shuo LiuDepartment of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Xi-Ming WangDepartment of Radiology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
Hua WuPathology Center and Department of Pathology, Soochow University, Suzhou 215123, China.
Wen-Juan GanDepartment of Pathology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China.
First Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aberrant expression of long noncoding RNAs (lncRNAs) is implicated in cancer development and progression. However, the clinical significance and mechanism by which NONHSAT062994 regulates colorectal cancer (CRC) is unknown. We here reported that NONHSAT062994 was significantly downregulated in human CRC tissues and cell lines. Moreover, its expression was inversely correlated with tumor size and overall survival (OS) time in CRC patients. In CRC cells, the overexpression and knockdown of NONHSAT062994 inhibited and enhanced CRC cell growth, respectively,

Indexed as

Akt signalingcolorectal cancergrowthLncRNA NONHSAT062994

Identifiers

PMID28978149
PMCPMC5620289
OpenAlexW2740175190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.