ArticleOncotarget2017
Nanofat-derived stem cells with platelet-rich fibrin improve facial contour remodeling and skin rejuvenation after autologous structural fat transplantation.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 7 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Autolougous platelet concentrates in esthetic medicine.Periodontology 2000 · 2025Pooled it
- Comparative Efficacy and Safety of Cell-Assisted and Conventional Lipotransfer in Facial Filling: A Systematic Review and Meta-Analysis.Aesthetic plastic surgery · 2024Pooled it
- Innovations in Skin and Soft Tissue Aging-A Systematic Literature Review and Market Analysis of Therapeutics and Associated Outcomes.Aesthetic plastic surgery · 2023Pooled it
- Supplementation of Facial Fat Grafting to Increase Volume Retention: A Systematic Review.Aesthetic surgery journal · 2022Pooled it
- Not Stromal Vascular Fraction (SVF) or Nanofat, but Total Stromal-Cells (TOST): A New Definition. Systemic Review of Mechanical Stromal-Cell Extraction Techniques.Tissue engineering and regenerative medicine · 2021Pooled it
- Effect of platelet-rich fibrin on cell proliferation, migration, differentiation, inflammation, and osteoclastogenesis: a systematic review of in vitro studies.Clinical oral investigations · 2020Pooled it
- Pooled it
- Nanofat for Injection Laryngoplasty: Office and Operative Results.Laryngoscope investigative otolaryngology · 2026Article
- Boosting the vascularization and regenerative capacity of nanofat by short-term ex vivo pretreatment with erythropoietin.Journal of translational medicine · 2026Article
- Systematic Review of Stem Cells in Plastic, Reconstructive, and Aesthetic Surgery: Clinical Application in Anti-Aging Medicine.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2026Review
- First comparison of commercial systems to prepare nanofat: technical performances and biological quality differ among obtained products.Scientific reports · 2026Article
- Immunohistochemical Analysis of Nanofat Membrane, Solid PRF, and Stromal Vascular Fraction Gel.Aesthetic plastic surgery · 2025Article
- Regenerative Nanofat Membrane Development Process.Aesthetic plastic surgery · 2025Article
- Current status of nanofat in the management of knee osteoarthritis: A systematic review.World journal of orthopedics · 2025Article
- Mechanical Fractionation of Adipose Tissue-A Scoping Review of Procedures to Obtain Stromal Vascular Fraction.Bioengineering (Basel, Switzerland) · 2023Article
- Nanofat in Plastic Reconstructive, Regenerative, and Aesthetic Surgery: A Review of Advancements in Face-Focused Applications.Journal of clinical medicine · 2023Review
- Research Progress on Preparation, Mechanism, and Clinical Application of Nanofat.Journal of burn care & research : official publication of the American Burn Association · 2022Review
- Advances in Fibrin-Based Materials in Wound Repair: A Review.Molecules (Basel, Switzerland) · 2022Review
- Adipose-Derived Stem Cells for Facial Rejuvenation.Journal of personalized medicine · 2022Review
- Autologous platelet concentrates for facial rejuvenation.Journal of applied oral science : revista FOB · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional autologous fat transplantation is a common surgical procedure for treating facial soft tissue depression and skin aging. However, the transplanted fat is easily absorbed, reducing the long-term efficacy of the procedure. Here, we examined the efficacy of nanofat-assisted autologous fat structural transplantation. Nanofat-derived stem cells (NFSCs) were isolated, mechanically emulsified, cultured, and characterized. Platelet-rich fibrin (PRF) enhanced proliferation and adipogenic differentiation of NFSCs
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.