ArticleOncotarget2017
Mean platelet volume, platelet distribution width and carcinoembryonic antigen to discriminate gastric cancer from gastric ulcer.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Upper Gastrointestinal Cancers: A Systematic Review.Advances in therapy · 2021Pooled it
- Prognostic Value and Clinicopathologic Features of Platelet Distribution Width in Cancer: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2018Pooled it
- Observational
- The importance of blood parameters in the detection of intestinal metaplasia and early diagnosis of gastric cancer.African health sciences · 2024Article
- Efficacy of circulating microRNA-130b and blood routine parameters in the early diagnosis of gastric cancer.Oncology letters · 2021Article
- Down regulation of miR-30a-5p and miR-182-5p in gastric cancer: Clinical impact and survival analysis.Biochemistry and biophysics reports · 2021Article
- Article
- Genetic platelet depletion is superior in platelet transfusion compared to current models.Haematologica · 2020Article
- Can mean platelet volume IndIcateActa clinica Croatica · 2019Review
- Mean platelet volume/platelet count ratio in colorectal cancer: a retrospective clinical study.BMC cancer · 2019Article
- The importance of complete blood count parameters in the screening of gastric cancer.Przeglad gastroenterologiczny · 2019Article
- Single and combined use of red cell distribution width, mean platelet volume, and cancer antigen 125 for differential diagnosis of ovarian cancer and benign ovarian tumors.Journal of ovarian research · 2018Article
- DcR3 combined with hematological traits serves as a valuable biomarker for the diagnosis of cancer metastasis.Oncotarget · 2017Article
- Elevated pretreatment platelet distribution width and platelet count predict poor prognosis in nasopharyngeal carcinoma.Oncotarget · 2017Article
- Article
- Lower mean platelet volume predicts poor prognosis in renal cell carcinoma.Scientific reports · 2017Article
- Diagnostic Value of Inflammation-Related Indicators in Distinguishing Early Colon Cancer and Adenomatous Polyps.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Activated platelets are involved in cancer development and progression. Mean platelet volume (MPV) and platelet distribution width (PDW) are early indexes of platelet activation. The objectives of this study were to investigate the ability of MPV, PDW and carcinoembryonic antigen (CEA) individually or in combination, to distinguish between gastric cancer and gastric ulcer. The study involved 194 patients with gastric cancer, 191 patients with gastric ulcer, and 185 control subjects. Subjects' characteristics and hematologic tests data at initial diagnosis were collected. We found that MPV levels are significantly increased and PDW levels are significantly reduced in patients with gastric ulcer and in control subjects compared with those in gastric cancer. When the area under the curve (AUC) was used to analyze control subjects
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Registered trials
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