ArticleOncotarget2017
Evaluation of hepatectomy and palliative local treatments for gastric cancer patients with liver metastases: a propensity score matching analysis.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Pooled it
- Are Palliative Interventions Worth the Risk in Advanced Gastric Cancer? A Systematic Review.Journal of clinical medicine · 2024Review
- Comprehensive treatment focusing on transarterial chemoembolization for postoperative liver metastasis in gastric cancer patients.American journal of translational research · 2024Article
- Survival Outcomes of Hepatectomy in Gastric Cancer Liver Metastasis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Effect of multimodal chemotherapy on survival of gastric cancer with liver metastasis - a population based analysis.Frontiers in oncology · 2023Article
- Prognostic factors and therapeutic effects of different treatment modalities for colorectal cancer liver metastases.World journal of gastrointestinal oncology · 2020Article
- A novel application of drug-eluting transarterial chemoembolization in treating non-liver cancers.Medicine · 2020Article
- Is there a role for treatment-oriented surgery in liver metastases from gastric cancer?World journal of clinical oncology · 2020Article
- Prognostic Factors After Hepatectomy for Gastric Adenocarcinoma Liver Metastases: Desmoplastic Growth Pattern as the Key to Improved Overall Survival.Cancer management and research · 2020Article
- Chinese consensus on the diagnosis and treatment of gastric cancer with liver metastases.Therapeutic advances in medical oncology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal treatments for gastric cancer with liver metastases (GCLM) remain controversial. This study aimed to evaluate the efficacy of hepatectomy, RFA and TACE as local treatments for GCLM.
methodsFrom 2001 to 2015, 119 consecutive patients who received multidisciplinary treatments based on curative gastrectomy and local treatments (hepatectomy, RFA and TACE) for liver metastases were enrolled in this retrospective cohort study. Patients were divided into Group A (46, hepatectomy) and Group B (73, either or both RFA and TACE). Propensity score matching analysis was employed.
resultsThe propensity model revealed that hepatectomy was associated with significantly longer OS compared with either or both RFA and TACE (P=0.021). The 1-, 3- and 5-year OS rates were 80.5%, 41.5% and 24.4%, respectively in Group A; and 85.4%, 21.9% and 12.2%, respectively in Group B. Subgroup analyses indicated that hepatectomy was associated with significantly longer long-term survival compared with TACE (P=0.033) and RFA (P=0.010). TACE had a similar efficacy as RFA (P=0.518), but with significantly lower costs (P=0.014) in for patients with metachronous GCLM.
conclusionHepatectomy is the optimal local treatment for GCLM when surgical R0 resection is intended. TACE attained a similar prognosis as RFA with relatively high cost-effectiveness, particularly for patients with metachronous GCLM.
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