The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

25 citing papers in PubMed.

1. A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.JCI insight · 2018
   Trial
2. The role of adipose tissue in critical illness-induced skeletal muscle wasting-new considerations for treatment approaches.Journal of applied physiology (Bethesda, Md. : 1985) · 2025
   Review
3. Therapeutic potential of natural products in inflammation: underlying molecular mechanisms, clinical outcomes, technological advances, and future perspectives.Inflammopharmacology · 2023
   Review
4. CLUSTERINg Circulating Histones in Sepsis.American journal of respiratory and critical care medicine · 2023
   Article
5. Anti-inflammatory activities of flavonoid derivates.ADMET & DMPK · 2023
   Review
6. HMGB1 Inhibition to Ameliorate Organ Failure and Increase Survival in Trauma.Biomolecules · 2022
   Article
7. Innate immunity and immunotherapy for hemorrhagic shock.Frontiers in immunology · 2022
   Review
8. Multi-Omics Techniques Make it Possible to Analyze Sepsis-Associated Acute Kidney Injury Comprehensively.Frontiers in immunology · 2022
   Review
9. Immunomonitoring of Monocyte and Neutrophil Function in Critically Ill Patients: From Sepsis and/or Trauma to COVID-19.Journal of clinical medicine · 2021
   Review
10. Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases.Acta pharmacologica Sinica · 2021
    Article
11. Multifaceted roles of Toll-like receptors in acute kidney injury.Heliyon · 2021
    Review
12. Therapeutic Potential of Mesenchymal Stromal Cell-Derived Extracellular Vesicles in the Prevention of Organ Injuries Induced by Traumatic Hemorrhagic Shock.Frontiers in immunology · 2021
    Review
13. Damage-associated molecular patterns in trauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020
    Review
14. Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis.Nature immunology · 2020
    Article
15. Targeting Purinergic Signaling in the Dynamics of Disease Progression in Sepsis.Frontiers in pharmacology · 2020
    Article
16. Circulating cell death biomarker TRAIL is associated with increased organ dysfunction in sepsis.JCI insight · 2019
    Article
17. Perspectives of New Advances in the Pathogenesis of Vitiligo: From Oxidative Stress to Autoimmunity.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Review
18. Potential Role of Flavonoids in Treating Chronic Inflammatory Diseases with a Special Focus on the Anti-Inflammatory Activity of Apigenin.Antioxidants (Basel, Switzerland) · 2019
    Review
19. Circulating RIPK3 levels are associated with mortality and organ failure during critical illness.JCI insight · 2018
    Article
20. Mechanisms and treatment of organ failure in sepsis.Nature reviews. Nephrology · 2018
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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