Evidence map›Paper›PMID 28977564›Full record

ArticleRheumatology (Oxford, England)2017

Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992-2013.

Dahai Yu, Kelvin P Jordan, John Bedson, Martin Englund, Fiona Blyth, Aleksandra Turkiewicz, Daniel Prieto-Alhambra, George Peat

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Rheumatology (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04956393 (Proof-of-Concept of the SOAR), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04956393 nacompletednot on this mapstarted 2021, after this paper: background citation

Proof-of-Concept of the SOAR (Stop OsteoARthritis) Program: A Randomized Delayed-Control Trial

TypeinterventionalSponsorUniversity of British ColumbiaRan2021 to 2023Enrolled58ConditionsArthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis KneeArmsImmediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Dahai YuResearch Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
Kelvin P JordanResearch Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
John BedsonResearch Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
Martin EnglundClinical Epidemiology Unit, Orthopaedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Fiona BlythConcord Clinical School, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia.
Aleksandra TurkiewiczClinical Epidemiology Unit, Orthopaedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Daniel Prieto-AlhambraGREMPAL (Grup de Recerca en Epidemiologia de les Malalties Prevalents de l'Aparell Locomotor), Idiap Jordi Gol Primary Care Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.
George PeatResearch Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
Keele University · GBLund University · SEUniversity of Oxford · GBUniversity of Sydney · AU

Funding

Medical Research Council G0501798
6 · The paper itself

Abstract

Objective: To determine recent trends in the rate and management of new cases of OA presenting to primary healthcare using UK nationally representative data. Methods: Using the Clinical Practice Research Datalink we identified new cases of diagnosed OA and clinical OA (including OA-relevant peripheral joint pain in those aged over 45 years) using established code lists. For both definitions we estimated annual incidence density using exact person-time, and undertook descriptive analysis and age-period-cohort modelling. Demographic characteristics and management were described for incident cases in each calendar year. Sensitivity analyses explored the robustness of the findings to key assumptions. Results: Between 1992 and 2013 the annual age-sex standardized incidence rate for clinical OA increased from 29.2 to 40.5/1000 person-years. After controlling for period effects, the consultation incidence of clinical OA was higher for successive cohorts born after the mid-1950s, particularly women. In contrast, with the exception of hand OA, we observed no increase in the incidence of diagnosed OA: 8.6/1000 person-years in 2004 down to 6.3 in 2013. In 2013, 16.4% of clinical OA cases had an X-ray referral. While NSAID prescriptions fell from 2004, the proportion prescribed opioid analgesia rose markedly (0.1% of diagnosed OA in 1992 to 1.9% in 2013). Conclusion: Rising rates of clinical OA, continued use of plain radiography and a shift towards opioid analgesic prescription are concerning. Our findings support the search for policies to tackle this common problem that promote joint pain prevention while avoiding excessive and inappropriate health care.

Indexed as

Primary Health CareAgedAged, 80 and overAge DistributionAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalCohort StudiesDatabases, FactualFemaleHumansIncidenceMaleMiddle AgedOsteoarthritisPopulation GrowthRadiographyAnalgesics, OpioidAnti-Inflammatory Agents, Non-Steroidalanalgesicsincidenceosteoarthritisprimary care

Identifiers

PMID28977564
PMCPMC5850125
OpenAlexW2743202802

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.