ArticleNucleic acids research2018
IMOTA: an interactive multi-omics tissue atlas for the analysis of human miRNA-target interactions.
Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Construction and Analysis of miRNA Regulatory Networks.Methods in molecular biology (Clifton, N.J.) · 2026Article
- MicroRNA-driven evolutionary pressure in SARS-CoV-2: the role of hsa-miR-6512 in mutational dynamics.Scientific reports · 2025Article
- Combination of CRP and miRNA signature as a potential diagnostic strategy for Kawasaki disease.Frontiers in pediatrics · 2025Article
- AmiCa: Atlas of miRNA-gene correlations in cancer.Computational and structural biotechnology journal · 2024Article
- The impact of host microRNAs on the development of conserved mutations of SARS-CoV-2.Scientific reports · 2024Article
- Systems Approaches to Cell Culture-Derived Extracellular Vesicles for Acute Kidney Injury Therapy: Prospects and Challenges.Function (Oxford, England) · 2024Review
- The hitchhikers' guide to RNA sequencing and functional analysis.Briefings in bioinformatics · 2023Article
- MicroRNA Regulatory Network Analysis Using miRNet 2.0.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Bioinformatics andInternational journal of ophthalmology · 2023Article
- TRmir: A Comprehensive Resource for Human Transcriptional Regulatory Information of MiRNAs.Frontiers in genetics · 2022Article
- miRTargetLink 2.0-interactive miRNA target gene and target pathway networks.Nucleic acids research · 2021Article
- In silico analysis suggests the RNAi-enhancing antibiotic enoxacin as a potential inhibitor of SARS-CoV-2 infection.Scientific reports · 2021Article
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- Article
- Conserved Genomic Terminals of SARS-CoV-2 as Coevolving Functional Elements and Potential Therapeutic Targets.mSphere · 2020Article
- Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting.International journal of molecular sciences · 2020Article
- Conserved Genomic Terminals of SARS-CoV-2 as Co-evolving Functional Elements and Potential Therapeutic Targets.bioRxiv : the preprint server for biology · 2020Article
- miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology.Nucleic acids research · 2020Article
- The microRNAs Regulating Vascular Smooth Muscle Cell Proliferation: A Minireview.International journal of molecular sciences · 2019Review
- Gastric Cancer MicroRNAs Meta-signature.International journal of molecular and cellular medicine · 2019Review
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7 authors.
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Abstract
Web repositories for almost all 'omics' types have been generated-detailing the repertoire of representatives across different tissues or cell types. A logical next step is the combination of these valuable sources. With IMOTA (interactive multi omics tissue atlas), we developed a database that includes 23 725 relations between miRNAs and 23 tissues, 310 932 relations between mRNAs and the same tissues as well as 63 043 relations between proteins and the 23 tissues in Homo sapiens. IMOTA also contains data on tissue-specific interactions, e.g. information on 331 413 miRNAs and target gene pairs that are jointly expressed in the considered tissues. By using intuitive filter and visualization techniques, it is with minimal effort possible to answer various questions. These include rather general questions but also requests specific for genes, miRNAs or proteins. An example for a general task could be 'identify all miRNAs, genes and proteins in the lung that are highly expressed and where experimental evidence proves that the miRNAs target the genes'. An example for a specific request for a gene and a miRNA could for example be 'In which tissues is miR-34c and its target gene BCL2 expressed?'. The IMOTA repository is freely available online at https://ccb-web.cs.uni-saarland.de/imota/.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.