Evidence map›Paper›PMID 28977210›Full record

ArticleArchives of endocrinology and metabolism

The role of moderate-to-vigorous physical activity in mediating the relationship between central adiposity and immunometabolic profile in postmenopausal women.

Tiego A Diniz, Fabricio E Rossi, Loreana S Silveira, Lucas Melo Neves, Ana Claudia de Souza Fortaleza, Diego G D Christofaro, Fabio S Lira, Ismael F Freitas-Junior

Abstract read
In one paragraph

Article in Archives of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Smartphone-Based Cancer and Obesity Prevention Education Program for Chinese Women (SCOPE): A Pilot RCT.International journal of environmental research and public health · 2023
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tiego A DinizUniversidade de São Paulo (USP), São Paulo, SP, Brasil.
Fabricio E RossiGrupo de Imunometabolismo e Exercício, Departamento de Educação Física, Universidade Estadual Paulista (Unesp), Presidente Prudente, SP, Brasil.
Loreana S SilveiraGrupo de Imunometabolismo e Exercício, Departamento de Educação Física, Universidade Estadual Paulista (Unesp), Presidente Prudente, SP, Brasil.
Lucas Melo NevesUniversidade de São Paulo (USP), São Paulo, SP, Brasil.
Ana Claudia de Souza FortalezaCentro de Estudos e Laboratório de Avaliação e Prescrição de Atividades Motoras (Celapam), Departamento de Educação Física, Unesp, Presidente Prudente, SP, Brasil.
Diego G D ChristofaroGrupo de Estudos em Atividade Física e Saúde, Departamento de Educação Física, Unesp, Presidente Prudente, SP, Brasil.
Fabio S LiraGrupo de Imunometabolismo e Exercício, Departamento de Educação Física, Universidade Estadual Paulista (Unesp), Presidente Prudente, SP, Brasil.
Ismael F Freitas-JuniorCentro de Estudos e Laboratório de Avaliação e Prescrição de Atividades Motoras (Celapam), Departamento de Educação Física, Unesp, Presidente Prudente, SP, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo analyze the role of moderate-to-vigorous physical activity (MVPA) in mediating the relationship between central adiposity and immune and metabolic profile in postmenopausal women. MATERIALS AND

methodsCross-sectional study comprising 49 postmenopausal women (aged 59.26 ± 8.32 years) without regular physical exercise practice. Body composition was measured by dual-energy X-ray absorptiometry. Fasting blood samples were collected for assessment of nonesterified fatty acids, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), adiponectin, insulin and estimation of insulin resistance (HOMA-IR). Physical activity level was assessed with an accelerometer (Actigraph GTX3x) and reported as a percentage of time spent in sedentary behavior and MVPA. All analyses were performed using the software SPSS 17.0, with a significance level set at 5%.

resultsSedentary women had a positive relationship between trunk fat and IL-6 (rho = 0.471; p = 0.020), and trunk fat and HOMA-IR (rho = 0.418; p = 0.042). Adiponectin and fat mass (%) were only positively correlated in physically active women (rho = 0.441; p = 0.027). Physically active women with normal trunk fat values presented a 14.7% lower chance of having increased HOMA-IR levels (β [95%CI] = 0.147 [0.027; 0.811]).

conclusionsThe practice of sufficient levels of MVPA was a protective factor against immunometabolic disorders in postmenopausal women.

Indexed as

ExerciseAbdominal FatAbsorptiometry, PhotonAdiponectinAdiposityAgedBody CompositionCross-Sectional StudiesFastingFatty AcidsFemaleFollicle Stimulating HormoneHumansInsulin ResistanceInterleukin-6Middle AgedAdiponectinFatty AcidsFollicle Stimulating HormoneIL6 protein, humanInterleukin-6

Identifiers

PMID28977210
PMCPMC10118934

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.