Evidence map›Paper›PMID 28976941›Full record

ArticleSensors (Basel, Switzerland)2017

Automated Dielectrophoretic Tweezers-Based Force Spectroscopy System in a Microfluidic Device.

Min Hyung Kim, Jeongjick Lee, Kihwan Nam, In Soo Park, Myeonggu Son, Hyunchul Ko, Sangyoup Lee, Dae Sung Yoon, Woo-Jin Chang, Sei Young Lee and 2 more

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Current Trends of Microfluidic Single-Cell Technologies.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Min Hyung KimDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. kmh900710@gmail.com.
Jeongjick LeeDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. wlslrbsl1@naver.com.
Kihwan NamBiomedical Research Institute, Korea Institute of Science and Technology, Seoul 136-791, Korea. kihwannam@gmail.com.
In Soo ParkDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. kojel84@gmail.com.
Myeonggu SonDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. s92624452@gmail.com.
Hyunchul KoDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. pakinsoo@hotmail.com.
Sangyoup LeeBiomedical Research Institute, Korea Institute of Science and Technology, Seoul 136-791, Korea. sangyoup@kist.re.kr.
Dae Sung YoonDepartment of Bio-Convergence, Korea University, Seoul 136-701, Korea. dsyoon@korea.ac.kr.
Woo-Jin ChangMechanical Engineering Department, University of Wisconsin-Milwaukee, 3200 N Cramer St., Milwaukee, WI 53211, USA. wjchang@uwm.edu.
Sei Young LeeDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. syl235@yonsei.ac.kr.
Young Ro YoonDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. yoon@yonsei.ac.kr.
Sang Woo LeeDepartment of Biomedical Engineering, Yonsei University, Wonju 220-710, Korea. yusuklee@yonsei.ac.kr.
Yonsei University · KRKorea Institute of Science and Technology · KRKorea University · KRUniversity of Wisconsin–Milwaukee · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We reported an automated dielectrophoretic (DEP) tweezers-based force spectroscopy system to examine intermolecular weak binding interactions, which consists of three components: (1) interdigitated electrodes and micro-sized polystyrene particles used as DEP tweezers and probes inside a microfluidic device, along with an arbitrary function generator connected to a high voltage amplifier; (2) microscopy hooked up to a high-speed charge coupled device (CCD) camera with an image acquisition device; and (3) a computer aid control system based on the LabVIEW program. Using this automated system, we verified the measurement reliability by measuring intermolecular weak binding interactions, such as hydrogen bonds and Van der Waals interactions. In addition, we also observed the linearity of the force loading rates, which is applied to the probes by the DEP tweezers, by varying the number of voltage increment steps and thus affecting the linearity of the force loading rates. This system provides a simple and low-cost platform to investigate intermolecular weak binding interactions.

Indexed as

dielectrophoresisforce loading rateforce spectroscopyintermolecular weak binding interactions

Identifiers

PMID28976941
PMCPMC5677021
OpenAlexW2762439378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.