ArticlePhysics in medicine and biology2017
Line focus x-ray tubes-a new concept to produce high brilliance x-rays.
Article in Physics in medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Is Ultrahigh Dose Rate Critical for the Effectiveness of Microbeam Radiation Therapy in a Broad-Beam Combined Treatment?Advances in radiation oncology · 2026Article
- The Potential of Dosimetry and the Visualization of Microbeam Arrays in NIPAM Gel at the PETRA III Synchrotron.Gels (Basel, Switzerland) · 2025Article
- Megavoltage photon FLASH for preclinical experiments.Medical physics · 2025Article
- Review
- Dosimetric characterization of a novel UHDR megavoltage X-ray source for FLASH radiobiological experiments.Scientific reports · 2024Article
- Novel unconventional radiotherapy techniques: Current status and future perspectives - Report from the 2nd international radiation oncology online seminar.Clinical and translational radiation oncology · 2023Article
- Good Timing Matters: The Spatially Fractionated High Dose Rate Boost Should Come First.Cancers · 2022Article
- Article
- Clinical microbeam radiation therapy with a compact source: specifications of the line-focus X-ray tube.Physics and imaging in radiation oncology · 2020Article
- A proof of principle experiment for microbeam radiation therapy at the Munich compact light source.Radiation and environmental biophysics · 2020Article
- High-resolution phase-contrast imaging of biological specimens using a stable betatron X-ray source in the multiple-exposure mode.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Currently hard coherent x-ray radiation at high photon fluxes can only be produced with large and expensive radiation sources, such as 3[Formula: see text] generation synchrotrons. Especially in medicine, this limitation prevents various promising developments in imaging and therapy from being translated into clinical practice. Here we present a new concept of highly brilliant x-ray sources, line focus x-ray tubes (LFXTs), which may serve as a powerful and cheap alternative to synchrotrons and a range of other existing technologies. LFXTs employ an extremely thin focal spot and a rapidly rotating target for the electron beam which causes a change in the physical mechanism of target heating, allowing higher electron beam intensities at the focal spot. Monte Carlo simulations and numeric solutions of the heat equation are used to predict the characteristics of the LFXT. In terms of photon flux and coherence length, the performance of the line focus x-ray tube compares with inverse Compton scattering sources. Dose rates of up to 180 Gy [Formula: see text] can be reached in 50 cm distance from the focal spot. The results demonstrate that the line focus tube can serve as a powerful compact source for phase contrast imaging and microbeam radiation therapy. The production of a prototype seems technically feasible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.