ArticleBosnian journal of basic medical sciences2018
Efficacy of a bundle approach in preventing the incidence of ventilator associated pneumonia (VAP).
Article in Bosnian journal of basic medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- The efficacy of subglottic secretion drainage in preventing ventilator-associated pneumonia in the intensive care unit: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Prevention of ventilator-associated pneumonia: intensive care nurses' perspectives and solution-oriented recommendations-a qualitative study.BMC nursing · 2026Article
- Reduced incidence of ventilator-associated pneumonia (VAP) at a tertiary care center due to enhanced compliance with evidence-based bundle care practices through structured training programs for ICU healthcare workers: a pilot study.GMS hygiene and infection control · 2026Article
- Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia: A Literature Review.Microorganisms · 2024Review
- Effect of fourth hourly oropharyngeal suctioning on ventilator-associated events in patients requiring mechanical ventilation in intensive care units of a tertiary care center in South India: a randomized controlled trial.Acute and critical care · 2023Article
- Prevention of ventilator-associated pneumonia through care bundles: A systematic review and meta-analysis.Journal of intensive medicine · 2023Article
- Influence of oral comprehensive nursing intervention on mechanically ventilated patients in ICU: a randimized controlled study.BMC nursing · 2023Article
- Antimicrobial stewardship in the intensive care unit.Journal of intensive medicine · 2023Review
- The Impact of Care Bundles on Ventilator-Associated Pneumonia (VAP) Prevention in Adult ICUs: A Systematic Review.Antibiotics (Basel, Switzerland) · 2023Review
- Impact of Rose Water Mouthwash on Prevention of Ventilator-Associated Pneumonia in Intensive Care Unit: A Randomized Controlled Trial.Tanaffos · 2023Article
- Bundle management strategy in reducing hospital-acquired pneumonia in hospitalized patients with mental disorders.Frontiers in psychiatry · 2023Article
- Prognosis of hospital-acquired pneumonia/ventilator-associated pneumonia with Stenotrophomonas maltophilia versus Klebsiella pneumoniae in intensive care unit: A retrospective cohort study.The clinical respiratory journal · 2022Article
- Analysis of risk factors for early-onset ventilator-associated pneumonia in a neurosurgical intensive care unit.BMC infectious diseases · 2022Article
- Exploring the Nursing Factors Related to Ventilator-Associated Pneumonia in the Intensive Care Unit.Frontiers in public health · 2022Article
- Risk Factors and Nursing Countermeasures of Ventilator-Associated Pneumonia in Children in the Intensive Care Unit.Journal of healthcare engineering · 2022Article
- Care bundles for improving outcomes in patients with COVID-19 or related conditions in intensive care - a rapid scoping review.The Cochrane database of systematic reviews · 2020Article
- Changes in immune indicators and bacteriologic profile were associated with patients with ventilator-associated pneumonia.Medicine · 2020Observational
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ventilator-associated pneumonia (VAP) is a potentially preventable iatrogenic illness that may develop following mechanical ventilation. A bundle for the prevention of VAP consists of different measures which may vary between institutions, and may include: elevation of the head of the bed, oral care with chlorhexidine, subglottic suctioning, daily assessment for extubation and the need for proton-pump inhibitors, use of closed suction systems, and maintaining endotracheal cuff pressure at 25 cmH2O. Our aim was to determine the efficacy of a VAP prevention bundle, consisting of the above-mentioned measures, by evaluating the incidence of VAP before (no-VAP-B group) and after (VAP-B group) the introduction of the bundle. We retrospectively evaluated the data for patients who were mechanically ventilated with an endotracheal tube, in the period between 1 September and 31 December 2014 (no-VAP-B group, n = 55, 54.5% males, mean age 67.8 ± 14.5 years) and between 1 January to 30 April 2015 (VAP-B group, n = 74, 62.1% males, mean age 64.8 ± 13.7 years). There were no statistically significant differences between no-VAP-B and VAP-B groups in demographic data, intensive care unit (ICU) mortality, hospital mortality, duration of ICU treatment, and duration of mechanical ventilation. No significant differences in the rates of VAP and early VAP (onset ≤7 days after intubation) were found between no-VAP-B and VAP-B groups (41.8% versus 25.7%, p = 0.06 and 10.9% versus 12.2%, p > 0.99, respectively). However, a significant decrease in the late VAP (onset >8 days after intubation) was found in VAP-B group compared to no-VAP-B group (13.5% versus 30.9%, p = 0.027). Overall, our results support the use of VAP prevention bundle in clinical practice.
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