Evidence map›Paper›PMID 28976803›Full record

ArticleVirulence2017

IP

Cecilia Li, Sophie Lev, Desmarini Desmarini, Keren Kaufman-Francis, Adolfo Saiardi, Ana P G Silva, Joel P Mackay, Philip E Thompson, Tania C Sorrell, Julianne T Djordjevic

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Cryptococcal nutrient acquisition and pathogenesis: dining on the host.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Arg1 frommBio · 2024
    Article
  7. Article
  8. Article
  9. Frontiers in cellular and infection microbiology · 2022
    Review
  10. Review
  11. IPmBio · 2020
    Article
  12. The Diverse Roles of Monocytes in Cryptococcosis.Journal of fungi (Basel, Switzerland) · 2020
    Review
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Cecilia Lia Centre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research , 176 Hawkesbury road, Westmead NSW 2145 , Australia.
Sophie Leva Centre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research , 176 Hawkesbury road, Westmead NSW 2145 , Australia.
Desmarini Desmarinia Centre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research , 176 Hawkesbury road, Westmead NSW 2145 , Australia.
Keren Kaufman-Francisa Centre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research , 176 Hawkesbury road, Westmead NSW 2145 , Australia.
Adolfo Saiardid Medical Research Council Laboratory for Molecular Cell Biology, University College London , Gower street, London WC1E 6BT , UK.
Ana P G Silvae School of Life and Environmental Sciences, The University of Sydney , Camperdown , NSW 2006 , Australia.
Joel P Mackaye School of Life and Environmental Sciences, The University of Sydney , Camperdown , NSW 2006 , Australia.
Philip E Thompsonf Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences , Monash University , 381 Royal Parade, Parkville , VIC 3052 , Australia.
Tania C Sorrella Centre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research , 176 Hawkesbury road, Westmead NSW 2145 , Australia.
Julianne T Djordjevica Centre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research , 176 Hawkesbury road, Westmead NSW 2145 , Australia.
The University of Sydney · AUWestmead Institute for Medical Research · AUMedical Research Council · GBMonash University · AUWestmead Hospital · AU

Funding

Medical Research Council MC_U122680443Medical Research Council MC_UU_00012/4Medical Research Council MC_UU_1201814Medical Research Council MC_UU_12018/4
6 · The paper itself

Abstract

We previously identified a series of inositol polyphosphate kinases (IPKs), Arg1, Ipk1, Kcs1 and Asp1, in the opportunistic fungal pathogen Cryptococcus neoformans. Using gene deletion analysis, we characterized Arg1, Ipk1 and Kcs1 and showed that they act sequentially to convert IP

Indexed as

AnimalsBacterial ProteinsCell WallCryptococcosisCryptococcus neoformansDisease Models, AnimalFemaleHomeostasisHumansInositol PhosphatesKineticsMiceMice, Inbred BALB CPhosphorylationPhosphotransferases (Alcohol Group Acceptor)VirulenceBacterial ProteinsInositol Phosphatesinositol polyphosphate multikinasePhosphotransferases (Alcohol Group Acceptor)cell wallCryptococcus neoformansinositol polyphosphate kinaseinositol pyrophosphateIP7meningitismolecular fungal pathogenesismouse modelPP-IP5virulence

Identifiers

PMID28976803
PMCPMC5810508
OpenAlexW2764239823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.