Evidence map›Paper›PMID 28976332›Full record

ArticleMolecular imaging and radionuclide therapy2017

Bone Single Photon Emission/Computed Tomography in the Detection of Sacroiliitis in Seronegative Spondyloarthritis: A Comparison with Magnetic Resonance Imaging.

Theodoros Pipikos, Dimitrios Kassimos, George Angelidis, John Koutsikos

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Molecular imaging and radionuclide therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06198361 (Value of Whole-body SPECT-CT CzT-based Camera), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06198361 completednot on this mapstarted 2021, after this paper: background citation

Value of Whole-body SPECT-CT CzT-based Camera (VERITON-CT) in the Assessment of Chronic Inflammatory Rheumatism With Axial Involvement (ASOCE)

TypeobservationalSponsorCentral Hospital, Nancy, FranceRan2021 to 2023Enrolled47ConditionsSpondyloarthritis
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Sacroiliitis - early diagnosis is key.Journal of inflammation research · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Theodoros Pipikos401 General Military Hospital, Clinic of Nuclear Medicine, Athens, Greece.
Dimitrios Kassimos401 General Military Hospital, Clinic of Rheumatology, Athens, Greece.
George AngelidisArmy Share Fund Hospital (417 NIMTS), Clinic of Nuclear Medicine, Athens, Greece.
John KoutsikosArmy Share Fund Hospital (417 NIMTS), Clinic of Nuclear Medicine, Athens, Greece.
401 General Military Hospital of Athens · GRNIMTS Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSeronegative spondyloarthritis (SpA) is characterized by chronic inflammation affecting the axial skeleton, entheses and occasionally peripheral joints. The involvement of the sacroiliac joints, sacroiliitis, is considered as a pathognomonic radiographic finding. Magnetic resonance imaging (MRI) is the method of choice for its early detection. Bone scintigraphy (BS) is characterized by high sensitivity in the diagnosis of bone and articular diseases. Limited value of BS in the diagnosis of sacroiliitis may be attributed to the use of planar imaging. In the present study, we aimed to investigate the role of SPECT in SpA, compared to MRI.

methodsForty-three patients suffering from inflammatory back pain underwent MRI evaluation of the sacroiliac joints and BS, combined with SPECT in the same region, for the assessment of sacroiliitis.

resultsBone SPECT revealed no findings of sacroiliitis in 11 patients, with total agreement with MRI. Findings of chronic lesions were demonstrated from both modalities in 2 patients. Bone SPECT and MRI findings were in concordance regarding the investigation of active sacroiliitis, with the exception of one patient with mild SPECT findings and negative MRI examination; the diagnosis of AS however, was established one year later, after a positive follow-up MRI. The evaluation of the planar imaging of the whole skeleton and SPECT imaging, revealed additional lesions.

conclusionBone SPECT is a reliable imaging method in the diagnosis of active sacroiliitis. Its application on planar BS, an economic and widely available diagnostic technique, appears to be a valuable aid for the clinician.

Indexed as

Bone scintigraphysacroiliitisSPECTspondyloarthritis magnetic resonance imaging.

Identifiers

PMID28976332
PMCPMC5643937
OpenAlexW2762956679

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.