Observational studyJournal of diabetes2018
Prepregnancy habitual intake of vitamin D from diet and supplements in relation to risk of gestational diabetes mellitus: A prospective cohort study.
Observational study in Journal of diabetes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Effectiveness of pre-pregnancy lifestyle in preventing gestational diabetes mellitus-a systematic review and meta-analysis of 257,876 pregnancies.Nutrition & diabetes · 2023Pooled it
- Maternal dietary components in the development of gestational diabetes mellitus: a systematic review of observational studies to timely promotion of health.Nutrition journal · 2023Pooled it
- Interventions to prevent women from developing gestational diabetes mellitus: an overview of Cochrane Reviews.The Cochrane database of systematic reviews · 2020Pooled it
- The role of vitamin D in the management and rehabilitation of gestational diabetes mellitus.Frontiers in nutrition · 2026Article
- Vitamin D on the susceptibility of gestational diabetes mellitus: a mini-review.Frontiers in nutrition · 2025Review
- Pre-pregnancy Diet to Maternal and Child Health Outcome: A Scoping Review of Current Evidence.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus.Medicina (Kaunas, Lithuania) · 2023Review
- Dietary Intake in Early Pregnancy and Glycemia in Late Pregnancy among Women with Obesity.Nutrients · 2021Article
- Nutrition as Prevention Factor of Gestational Diabetes Mellitus: A Narrative Review.Nutrients · 2021Review
- Improvement Effect of Metformin on Female and Male Reproduction in Endocrine Pathologies and Its Mechanisms.Pharmaceuticals (Basel, Switzerland) · 2021Review
- The relationship among vitamin D, TLR4 pathway and preeclampsia.Molecular biology reports · 2020Review
- Changes in Micronutrient Intake and Status, Diet Quality and Glucose Tolerance from Preconception to the Second Trimester of Pregnancy.Nutrients · 2019Article
- Polysaccharide IV fromFrontiers in endocrinology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundVitamin D may play a pivotal role in regulating insulin secretion and insulin sensitivity. However, the effect of vitamin D intake, either from the diet or from supplements, on the development of gestational diabetes mellitus (GDM) remains unclear. We prospectively examined the association of prepregnancy habitual intake of vitamin D from diet and supplements with the risk of incident GDM in a well-established cohort.
methodsThe present study was performed on 21 356 singleton pregnancies from 15 225 women in the Nurses' Health Study II cohort. Diet information, including vitamin D intake from food sources and supplements, was assessed in 1991 and every 4 years thereafter by validated food frequency questionnaires. Log-binomial models with generalized estimating equations were used to estimate relative risks (RRs) and 95% confidence intervals (CIs).
resultsDuring 10 years of follow-up, 865 incident GDM cases were documented. After adjustment for age, parity, race/ethnicity, family history of diabetes, dietary and lifestyle factors, and body mass index, the RRs (95% CIs) of GDM risk associated with supplemental vitamin D intake of 0, 1-399, and ≥400 IU/day were 1.00 (reference), 0.80 (0.67-0.96), and 0.71 (0.56-0.90), respectively (P
conclusionsPrepregnancy supplemental vitamin D intake was significantly and inversely associated with risk of GDM. This study indicates potential benefits of increasing vitamin D intake from supplements in the prevention of GDM in women of reproductive age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.