Evidence map›Paper›PMID 28976016›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2017

Pedestrian safety in patients with Parkinson's disease: A case-control study.

Kristin J Ford, Allen Joop, Raima A Memon, Kimberly H Wood, Karlene Ball, Gary R Cutter, David C Schwebel, Amy W Amara

Open access · greenAbstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kristin J FordDepartment of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Allen JoopDepartment of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Raima A MemonDepartment of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Kimberly H WoodDepartment of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Karlene BallDepartment of Psychology, Edward R. Roybal Center for Translational Research on Aging and Mobility University of Alabama at Birmingham, Birmingham, Alabama, USA.
Gary R CutterDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
David C SchwebelDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Amy W AmaraDepartment of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · US

Funding

Research Education CoreP30AG031054 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DURANT, RAEGAN WINSTON · 2007 to 2025
$11.6M
NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
Pilot CoreP30AG022838 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALL, KARLENE K · 2003 to 2020
$5.7M
Interdisciplinary Training in Pathobiology and Rehabilitation Medicine.T32HD071866 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAMES RIMMER, Anna E. Thalacker-Mercer · 2012 to 2026
$4.8M
Predicting Long-Term Mobility Outcomes for Older AdultsR01AG021958 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALL, KARLENE K · 2003 to 2014
$4.0M
The Effect of Low Frequency STN DBS on Sleep and Vigilance in PD PatientsK23NS080912 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMARA, AMY WILLIS · 2012 to 2016
$934k
Yale University Clinical and Translational Science Award ProgramTL1TR000141 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$720k
NCATS NIH HHS TL1 TR000141NCATS NIH HHS TL1 TR001864NIA NIH HHS P30 AG022838NIA NIH HHS P30 AG031054NIA NIH HHS R01 AG021958NICHD NIH HHS T32 HD071866NINDS NIH HHS K23 NS080912
6 · The paper itself

Abstract

backgroundPatients with Parkinson's disease experience debilitating motor symptoms as well as nonmotor symptoms, such as cognitive dysfunction and sleep disorders. This constellation of symptoms has the potential to negatively influence pedestrian safety. The objective of this study was to investigate the association of motor symptoms, daytime sleepiness, impaired vigilance, and cognitive dysfunction with pedestrian behavior in patients with Parkinson's disease and healthy older adults.

methodsFifty Parkinson's disease and 25 control participants were evaluated within a virtual reality pedestrian environment and completed assessments of motor performance, daytime sleepiness (Epworth Sleepiness Scale), vigilance (psychomotor vigilance task), and visual processing speed (Useful Field of View) outside the virtual reality environment. The primary outcome measure was time to contact, defined as the time remaining until a participant would have been hit by an approaching vehicle while crossing the virtual street.

resultsThe virtual reality pedestrian environment was feasible in all participants. Patients with Parkinson's disease demonstrated riskier pedestrian behavior compared with controls. Among Parkinson's disease participants, walking speed, objective measures of vigilance, and visual processing speed were correlated with pedestrian behavior, with walking speed the strongest predictor of time to contact, explaining 48% of the variance. Vigilance explained an additional 8% of the variance. In controls, vigilance was also important for street-crossing safety, but older age was the most robust predictor of pedestrian safety.

conclusionsWalking speed is associated with unsafe pedestrian behavior in patients with Parkinson's disease. In contrast, age was the strongest predictor of pedestrian safety in healthy older adults. © 2017 International Parkinson and Movement Disorder Society.

Indexed as

PedestriansSafetyAgedAge FactorsAttentionAttention Deficit Disorder with HyperactivityCase-Control StudiesCross-Sectional StudiesDisorders of Excessive SomnolenceFemaleHumansMaleMiddle AgedParkinson DiseaseVirtual RealityWalkingParkinson's diseasesafety: visual processingvigilancevirtual reality

Identifiers

PMID28976016
PMCPMC5732050
OpenAlexW2761754000

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.