Evidence map›Paper›PMID 28975929›Full record

ReviewNature reviews. Clinical oncology2017

Radiomics: the bridge between medical imaging and personalized medicine.

Philippe Lambin, Ralph T H Leijenaar, Timo M Deist, Jurgen Peerlings, Evelyn E C de Jong, Janita van Timmeren, Sebastian Sanduleanu, Ruben T H M Larue, Aniek J G Even, Arthur Jochems and 10 more

5 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 3,336 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3,336citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03373123 nawithdrawnnot on this map

Radiomics-based Surrogate of Endoscopy (rEndosc) for Noninvasive Prediction of Esophageal Varices and Risk Stratification of Variceal Hemorrhage in Hepatitis B Virus-related Cirrhosis (CHESS1703)

TypeinterventionalSponsorNanfang Hospital, Southern Medical UniversityRan2017 to 2018Enrolled0ConditionsEsophageal Varices in Cirrhosis of the LiverArmsEndoscopy, CTA
NCT03766880 nacompletednot on this mapstarted 2018, after this paper: background citation

MR-based Models for Noninvasive Detection of Clinically Significant Portal Hypertension in Cirrhosis (CHESS1802)

TypeinterventionalSponsorNanfang Hospital, Southern Medical UniversityRan2018 to 2019Enrolled175ConditionsHypertension, PortalArmsTransjugular HVPG measurement, MR imaging
NCT06084195 narecruitingnot on this mapstarted 2023, after this paper: background citation

Unravelling Tumour Biology In Ovarian Cancer With Precision Imaging

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2023 to 2029Enrolled120ConditionsHigh Grade Serous Ovarian CancerArmsBlood sample and tissue sample
NCT06108310 unknown statusnot on this mapstarted 2021, after this paper: background citation

ATTRACT - ArTificial inTelligence-based RAdiogenomics in Colon Tumors

TypeobservationalSponsorUniversity of Roma La SapienzaRan2021 to 2025Enrolled500ConditionsColon Cancer Stage II, Colon Cancer Stage III
NCT07075679 narecruitingnot on this mapstarted 2025, after this paper: background citation

Use of Artificial Intelligence in Breast Cancer Screening: Impact of AI-Assisted Single Reading by One Radiologist on Screening Quality Indicators Compared to Standard Double Reading by Two Radiologists Without AI

TypeinterventionalSponsorUniversity Hospital OlomoucRan2025 to 2028Enrolled8,000ConditionsBreast Cancer Screening, Artificial Intelligence (AI), Breast Cancer Screening and DiagnosisArmsGroup with AI iCAD version 3, Group without AI
3 · Its place in the literature

Who cites it

3,336 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  4. PET-CT radiomics and artificial intelligence for predicting lymph node metastasis in cervical cancer: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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3,276 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Philippe LambinThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Ralph T H LeijenaarThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Timo M DeistThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Jurgen PeerlingsThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Evelyn E C de JongThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Janita van TimmerenThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Sebastian SanduleanuThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Ruben T H M LarueThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Aniek J G EvenThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Arthur JochemsThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Yvonka van WijkThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Henry WoodruffThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Johan van SoestDepartment of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Doctor Tanslaan 12, 6229 ET, Maastricht, The Netherlands.
Tim LustbergDepartment of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Doctor Tanslaan 12, 6229 ET, Maastricht, The Netherlands.
Erik RoelofsThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Wouter van ElmptDepartment of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Doctor Tanslaan 12, 6229 ET, Maastricht, The Netherlands.
Andre DekkerDepartment of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Doctor Tanslaan 12, 6229 ET, Maastricht, The Netherlands.
Felix M MottaghyDepartment of Radiology and Nuclear Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Doctor Tanslaan 12, 6229 ET, Maastricht, The Netherlands.
Joachim E WildbergerDepartment of Radiology and Nuclear Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Doctor Tanslaan 12, 6229 ET, Maastricht, The Netherlands.
Sean WalshThe D-Lab: Decision Support for Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiomics, the high-throughput mining of quantitative image features from standard-of-care medical imaging that enables data to be extracted and applied within clinical-decision support systems to improve diagnostic, prognostic, and predictive accuracy, is gaining importance in cancer research. Radiomic analysis exploits sophisticated image analysis tools and the rapid development and validation of medical imaging data that uses image-based signatures for precision diagnosis and treatment, providing a powerful tool in modern medicine. Herein, we describe the process of radiomics, its pitfalls, challenges, opportunities, and its capacity to improve clinical decision making, emphasizing the utility for patients with cancer. Currently, the field of radiomics lacks standardized evaluation of both the scientific integrity and the clinical relevance of the numerous published radiomics investigations resulting from the rapid growth of this area. Rigorous evaluation criteria and reporting guidelines need to be established in order for radiomics to mature as a discipline. Herein, we provide guidance for investigations to meet this urgent need in the field of radiomics.

Indexed as

Decision Support TechniquesClinical Decision-MakingData MiningDiagnostic ImagingDiffusion of InnovationHumansNeoplasmsPatient-Specific ModelingPrecision MedicinePredictive Value of TestsPrognosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.