Evidence map›Paper›PMID 28975466›Full record

ArticleObesity surgery2018

Diabetes Outcomes More than a Decade Following Sustained Weight Loss After Laparoscopic Adjustable Gastric Band Surgery.

John M Wentworth, Chloe Cheng, Cheryl Laurie, Stewart Skinner, Paul R Burton, Wendy A Brown, Paul E O'Brien

Registry-linked trialAbstract read
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In one paragraph

Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03643783 (Impact of Plasma Soluble Prorenin Receptor in Obese and Type 2 Diabetic Patients), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03643783 completednot on this map

Impact of Plasma Soluble Prorenin Receptor in Obese and Type 2 Diabetic Patients

TypeobservationalSponsorTulane UniversityRan2018 to 2019Enrolled10ConditionsObesity, Type2 Diabetes, Bariatric Surgery Candidate
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John M WentworthMonash University Centre for Obesity Research and Education, Melbourne, VIC, Australia. wentworth@wehi.edu.au.ORCID 0000-0002-5197-3529
Chloe ChengMonash University Centre for Obesity Research and Education, Melbourne, VIC, Australia.
Cheryl LaurieMonash University Centre for Obesity Research and Education, Melbourne, VIC, Australia.
Stewart SkinnerMonash University Centre for Obesity Research and Education, Melbourne, VIC, Australia.
Paul R BurtonMonash University Centre for Obesity Research and Education, Melbourne, VIC, Australia.
Wendy A BrownMonash University Centre for Obesity Research and Education, Melbourne, VIC, Australia.
Paul E O'BrienMonash University Centre for Obesity Research and Education, Melbourne, VIC, Australia.
Monash University · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term outcome data are needed to define the role of bariatric surgery in type 2 diabetes (T2D). To address this, we collated diabetes outcomes more than a decade after laparoscopic adjustable gastric band (LAGB) surgery.

methodClinical and biochemical measures from 113 obese T2D patients who underwent LAGB surgery in 2003 and 2004 were analyzed. Diabetes remission was defined as HbA1c < 6.2% (44 mmol/mol) and fasting glucose < 7.0 mmol/L.

resultsSeventy-nine patients had weight data at 10 years and attained a median [Q1, Q3] weight loss of 16 [10, 21] percent. Sixty patients attended a follow-up assessment. Their baseline HbA1c of 7.8 [7.1, 9.3] percentage units (62 [54, 78] mmol/mol) had decreased to 6.6 [6.1, 8.4] (49 [43, 68] mmol/mol) despite no significant change in glucose-lowering therapy. Eleven patients (18%) were in diabetes remission and another 18 had HbA1c ≤ 6.5%. Significant improvements in physical measures of quality of life, blood pressure, and lipid profile were also observed but there was no change in the proportion of patients with albuminuria and a significant decline in estimated glomerular filtration rate. Twelve patients in the follow-up cohort (20%) required anti-reflux medication after surgery and 26 (43%) underwent gastric band revision surgery.

conclusionWeight loss for over 10 years after LAGB surgery delivers clinically meaningful improvements in HbA1c, blood pressure, lipids, and quality of life at the cost of a high rate of revision surgery and increased use of anti-reflux medication. These findings support the use of bariatric surgery as a long-term treatment for weight loss and wellbeing in patients with T2D. STUDY REGISTRATION: Registered with the Australian Clinical trials registry as ACTRN12615000089538.

Indexed as

AdultAustraliaDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGastroplastyHumansLaparoscopyMaleMiddle AgedObesityQuality of LifeReoperationRetrospective StudiesTreatment OutcomeWeight LossBariatric surgeryLaparoscopic adjustable gastric bandLong-termObesityOutcomesQuality of lifeType 2 diabetes

Identifiers

PMID28975466
OpenAlexW2762150519

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.