Evidence map›Paper›PMID 28974947›Full record

ReviewFrontiers in microbiology2017

Fungal Lactamases: Their Occurrence and Function.

Minglu Gao, Anthony E Glenn, Alex A Blacutt, Scott E Gold

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Response of Fusarium oxysporum soil isolate to amphotericin B and fluconazole at the proteomic level.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  6. Journal of fungi (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Crystal structure of a polyglycine hydrolase determined using a RoseTTAFold model.Acta crystallographica. Section D, Structural biology · 2023
    Article
  9. Article
  10. Article
  11. Transcriptomic Response ofFrontiers in fungal biology · 2022
    Article
  12. Transcriptomic Responses ofFrontiers in fungal biology · 2022
    Article
  13. Global Changes in AsexualMicroorganisms · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. The Transcriptional Profile ofPathogens (Basel, Switzerland) · 2019
    Article
  19. Past and Present Perspectives on β-Lactamases.Antimicrobial agents and chemotherapy · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Minglu GaoDepartment of Plant Pathology, The University of Georgia, AthensGA, United States.
Anthony E GlennToxicology and Mycotoxin Research Unit, U.S. National Poultry Research Center, United States Department of Agriculture - Agricultural Research Service, AthensGA, United States.
Alex A BlacuttDepartment of Plant Pathology, The University of Georgia, AthensGA, United States.
Scott E GoldToxicology and Mycotoxin Research Unit, U.S. National Poultry Research Center, United States Department of Agriculture - Agricultural Research Service, AthensGA, United States.
University of Georgia · USAgricultural Research Service · USUnited States Department of Agriculture · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi are absorptive feeders and thus must colonize and ramify through their substrate to survive. In so doing they are in competition, particularly in the soil, with myriad microbes. These microbes use xenobiotic compounds as offensive weapons to compete for nutrition, and fungi must be sufficiently resistant to these xenobiotics. One prominent mechanism of xenobiotic resistance is through production of corresponding degrading enzymes. As typical examples, bacterial β-lactamases are well known for their ability to degrade and consequently confer resistance to β-lactam antibiotics, a serious emerging problem in health care. We have identified many fungal genes that putatively encode proteins exhibiting a high degree of similarity to β-lactamases. However, fungal cell walls are structurally different from the bacterial peptidoglycan target of β-lactams. This raises the question, why do fungi have lactamases and what are their functions? Previously, we identified and characterized one

Indexed as

fungiFusarium verticillioideslactamssoilβ-lactamases

Identifiers

PMID28974947
PMCPMC5610705
OpenAlexW2755764398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.