Evidence map›Paper›PMID 28974930›Full record

ArticleFrontiers in pharmacology2017

Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from

Arnaud F Kouam, Fei Yuan, Frédéric N Njayou, Hongtao He, Roméo F Tsayem, Babayemi O Oladejo, Fuhang Song, Paul F Moundipa, George F Gao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. IBRO neuroscience reports · 2025
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  3. Delayed treatment with hydro-ethanolic extract ofPharmaceutical science advances · 2024
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  10. Acetaminophen-induced apoptosis: Facts versus fiction.Journal of clinical and translational research · 2020
    Review
  11. Article
  12. Hyperoside alleviatedInternational journal of clinical and experimental pathology · 2019
    Article
  13. Inhibitory activity of limonoids fromAvicenna journal of phytomedicine
    Article
  14. Extracts ofAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Arnaud F KouamLaboratory of Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé 1Yaoundé, Cameroon.
Fei YuanCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of SciencesBeijing, China.
Frédéric N NjayouLaboratory of Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé 1Yaoundé, Cameroon.
Hongtao HeCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of SciencesBeijing, China.
Roméo F TsayemLaboratory of Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé 1Yaoundé, Cameroon.
Babayemi O OladejoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of SciencesBeijing, China.
Fuhang SongCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of SciencesBeijing, China.
Paul F MoundipaLaboratory of Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé 1Yaoundé, Cameroon.
George F GaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of SciencesBeijing, China.
Chinese Academy of Sciences · CNInstitute of Microbiology · CNUniversité de Yaoundé I · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced liver injury (DILI) is a major clinical problem where natural compounds hold promise for its abrogation.

Indexed as

acetaminophenhepatoprotectionK. grandifoliolalimonoidsMkp-1Nrf2

Identifiers

PMID28974930
PMCPMC5610691
OpenAlexW2755236483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.