ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2017
Difference Between Cryotherapy and Follow Up Low Grade Squamous Lesion of Cervix Uteri.
Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Evaluating HPV E6/E7 mRNA expression and genotype prevalence in cervical cytology and biopsy samples from Yunnan Province, China.Ecancermedicalscience · 2025Article
- HPV-Related Cancers in Bosnia and Herzegovina: A Comprehensive Review.Acta medica academica · 2024Review
- Transcription factor c-Rel regulated by E5 affects the whole process after HPV16 infection through miR-133a-modulated feedback loop aim at mir-379-369 cluster.Cancer cell international · 2022Article
- Cytological, Colposcopic and Pathohistological Correlation of HSIL and ASC H Findings.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2020Article
- Progression Low Squamous Intraepithelial Lesion and Human Papillomavirus Infections.Materia socio-medica · 2020Article
- Cryotherapy of Genital Warts.Materia socio-medica · 2019Article
- Cryotherapy of Erosion of Cervix and Low Grade Squamous Intraepithelial Lesion.Materia socio-medica · 2018Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCervical cancer can be successfully prevented by effective treatment.
aimAnalyse of success of cryotherapy in LSIL and ASCUS. MATERIALS ET
methodsIn retrospective study between January 2016 to March 2017, 3244 PAP test were analysed. 257 patients who had been diagnosed with LSIL and ASCUS from PAP smear were divided in two groups: women who had HPV positive, colposcopic positive and cytologic finding of LSIL or ASCUS treathed with cryotherapy and women with LSIL, ASCUS and negative colposcopy. χ
resultsAnalysis of 3244 PAP smears showed negative for intraepithelial lesion or malignancy (NILM) in 90,10% (N-2923), and abnormal in 9,8% (N-321) of women. ASCUS was found in 4,8% (N-156) and ASC-H in 0,2% (N-6), LSIL in 3,1% (N-101), HSIL in 0,64% (N-21). The average age of patients with ASCUS lesion was 41 ± 12 years. After cryotherapy, HSIL had progression in 1,5% (N-1), persistence in 6,3% (N-4) and regression in 91,7% (N-58). Progression occured in 10,5% (N-4) of HSIL, persistence in 52,6% (N-20) and regression in 36,7% (N-14) in 38 women with LSIL lesion after repeated PAP test. Progression occured in 8% (N-10) of LSIL and 4% HSIL (N-5), persistence in 58% (N-72) and regression in 29,8% (N-37) in 124 women with ASCUS lesion after treatment and repeated PAP test. Difference in progression lesions in HSIL between women with cryotherapy (1,5%) and follow-up (10,5%) after LSIL is not significant, but progression to CIN II occured after cryotherapy. CIN III or cervical cancer was not found.
conclusionCryotherapy prevents progression of LSIL in HSIL and in cervical cancer. Because of that cryotherapy is successful method in prevention of cervical cancer.
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