Evidence map›Paper›PMID 28974648›Full record

ArticleThorax2018

Prevalence of asthma-like symptoms with ageing.

Debbie Jarvis, Roger Newson, Christer Janson, Angelo Corsico, Joachim Heinrich, Josep M Anto, Michael J Abramson, Anne-Marie Kirsten, Jan Paul Zock, Roberto Bono and 20 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Thorax, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 20 institutions in 15 countries.

Debbie JarvisPopulation Health and Occupational Disease, National Heart and Lung Institute, Imperial College, London, UK.ORCID 0000-0002-1753-3896
Roger NewsonDepartment of Primary Care and Public Health, Imperial College London, London, UK.
Christer JansonDepartment of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
Angelo CorsicoDivision of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Joachim HeinrichInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Clinical Center, Ludwig Maximilian University, Comprehensive Pneumology Centre Munich, German Centre for Lung Research, Muenchen, Germany.
Josep M AntoISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Michael J AbramsonSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Anne-Marie KirstenPulmonary Research Institute at Lung Clinic Grosshansdorf, Grosshansdorf, Germany.
Jan Paul ZockISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Roberto BonoDepartment of Public Health and Pediatrics, University of Turin, Turin, Italy.
Pascal DemolyUniversity Hospital of Montpellier, Montpellier, France.
Bénédicte LeynaertInserm UMR 1152-Equipe Epidémiologie, Université Paris Diderot, Paris, France.
Chantal RaherisonInserm-U1219 Bordeaux Population Health Research Center, Bordeaux University, Bordeaux, France.
Isabelle PinINSERM, IAB, Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, Grenoble, France.
Thorarinn GislasonDepartment of Respiratory Medicine and Sleep, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
Rain JogiTartu University Hospital, Lung Clinic, Estonia, Europe.
Vivi SchlunssenDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Cecilie SvanesCentre for International Health, University of Bergen, Bergen, Norway.
John WatkinsPublic Health Wales, Cardiff, Wales.
Joost WeylerDepartment of Epidemiology and Social Medicine (ESOC), Faculty of Medicine and Health Sciences, StatUA Statistics Centre, University of Antwerp, Antwerp, Belgium.
Antonio Pereira-VegaRespiratory and Allergy Clinical Unit, Universitary Hospitalary Complex, Huelva, Spain.
Isabel UrrutiaDepartment of Respiratory, Galdakao Hospital, Galdakao, Spain.
Jose A GullónServicio Neumología, Hospital Universitario San Agustín, Avilés, Spain.
Bertil ForsbergPublic Health and Clinical Medicine, Occupational and Environmental Medicine, University of Umea, Umea, Sweden.
Nicole Probst-HenschDepartment Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
H Marike BoezenDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Jesús Martinez-Moratalla RoviraServicio de Neumología, Complejo Hospitalario Universitario, Albacete, Spain.
Simone AccordiniUnit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
Roberto de MarcoUnit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
Peter BurneyPopulation Health and Occupational Disease, National Heart and Lung Institute, Imperial College, London, UK.
Imperial College London · GBInserm · FRUniversitat Pompeu Fabra · ESUniversity of Verona · ITAarhus University · DKComplejo Hospitalario Universitario de Albacete · ESGerman Center for Lung Research · DEHaukeland University Hospital · NOHospital de Galdakao · ESHospital Universitario San Agustín · ESLungenClinic Grosshansdorf · DEMonash University · AUPublic Health Wales · GBSorbonne Université · FRSwiss Tropical and Public Health Institute · CHTartu University Hospital · EEUmeå University · SEUniversity Medical Center Groningen · NLUniversity of Antwerp · BEUniversity of Iceland · IS

Funding

Basal Ganglia and 5-HT in Ritualistic Social DisplaysR01MH062633 · NIMH · UNIVERSITY OF FLORIDA · PI BAXTER, LEWIS R · 2001 to 2005
$1.4M
Department of HealthMedical Research Council G0901214NIMH NIH HHS R01 MH062633Wellcome Trust
6 · The paper itself

Abstract

backgroundChange in the prevalence of asthma-like symptoms in populations of ageing adults is likely to be influenced by smoking, asthma treatment and atopy.

methodsThe European Community Respiratory Health Survey collected information on prevalent asthma-like symptoms from representative samples of adults aged 20-44 years (29 centres in 13 European countries and Australia) at baseline and 10 and 20 years later (n=7844). Net changes in symptom prevalence were determined using generalised estimating equations (accounting for non-response through inverse probability weighting), followed by meta-analysis of centre level estimates.

findingsOver 20 years the prevalence of 'wheeze' and 'wheeze in the absence of a cold' decreased (-2.4%, 95% CI -3.5 to -1.3%; -1.5%, 95% CI -2.4 to -0.6%, respectively) but the prevalence of asthma attacks, use of asthma medication and hay fever/nasal allergies increased (0.6%, 95% CI 0.1 to 1.11; 3.6%, 95% CI 3.0 to 4.2; 2.7%, 95% CI 1.7 to 3.7). Changes were similar in the first 10 years compared with the second 10 years, except for hay fever/nasal allergies (increase seen in the first 10 years only). Decreases in these wheeze-related symptoms were largely seen in the group who gave up smoking, and were seen in those who reported hay fever/nasal allergies at baseline.

interpretationEuropean adults born between 1946 and 1970 have, over the last 20 years, experienced less wheeze, although they were more likely to report asthma attacks, use of asthma medication and hay fever. Decrease in wheeze is largely attributable to smoking cessation, rather than improved treatment of asthma. It may also be influenced by reductions in atopy with ageing.

Indexed as

AdultAge FactorsAsthmaAustraliaCohort StudiesEuropeFemaleHealth SurveysHumansMalePrevalenceRespiratory SoundsRhinitis, Allergic, SeasonalYoung AdultAsthma Epidemiology

Identifiers

PMID28974648
PMCPMC5738606
OpenAlexW2763333385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.