Evidence map›Paper›PMID 28974555›Full record

ArticleRNA (New York, N.Y.)2018

Orchestrated positioning of post-transcriptional modifications at the branch point recognition region of U2 snRNA.

Svetlana Deryusheva, Joseph G Gall

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Stable lariats bearing a snoRNA (slb-snoRNA) in eukaryotic cells: A level of regulation for guide RNAs.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  3. Article
  4. Article
  5. Spliceosomal snRNA Epitranscriptomics.Frontiers in genetics · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Svetlana DeryushevaDepartment of Embryology, Carnegie Institution for Science, Baltimore, Maryland 21218, USA.
Joseph G GallDepartment of Embryology, Carnegie Institution for Science, Baltimore, Maryland 21218, USA.ORCID 0000-0001-9664-6559
Carnegie Institution for Science · US

Funding

THE ORGANIZATION OF ANIMAL CELL NUCLEIR01GM033397 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI GALL, JOSEPH G. · 1985 to 2019
$8.4M
NIGMS NIH HHS R01 GM033397
6 · The paper itself

Abstract

The branch point recognition region of spliceosomal snRNA U2 is heavily modified post-transcriptionally in most eukaryotic species. We focused on this region to learn how nearby positions may interfere with each other when targeted for modification. Using an in vivo yeast

Indexed as

RNA Processing, Post-TranscriptionalAnimalsBase SequenceBinding SitesCaenorhabditis elegansDrosophila melanogasterHeLa CellsHumansMicePseudouridineRNA, Small NuclearSaccharomyces cerevisiaeXenopusPseudouridineRNA, Small NuclearU2 small nuclear RNA2′-O-methylationguide RNApseudouridylationU2 snRNAU5 snRNA

Identifiers

PMID28974555
PMCPMC5733568
OpenAlexW2763216776

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.