ArticleJournal of the American Heart Association2017
Sex Differences in Circulating Progenitor Cells.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 49 citations in OpenAlex.
- Heart failure with preserved ejection fraction: The role of intravascular volumes and body composition in exercise-induced progenitor cell mobilization.International journal of cardiology. Heart & vasculature · 2026Article
- Acute High Intensity Interval Exercise Promotes Circulating Progenitor Cell Mobilization and Improves Microcirculation in Patients with Chronic Heart Failure.Journal of cardiovascular development and disease · 2026Article
- Bone Marrow Niche in Cardiometabolic Disease: Mechanisms and Therapeutic Potential.Circulation research · 2025Review
- Cancer therapy-related cardiovascular aging: mechanisms, monitoring, and intervention strategies.Frontiers in cardiovascular medicine · 2025Review
- Senolysis potentiates endothelial progenitor cell adhesion to and integration into the brain vasculature.Stem cell research & therapy · 2024Article
- Sex-dependent niche responses modulate steady-state and regenerative hematopoiesis.Experimental hematology · 2024Article
- Circulating Progenitor Cells and Coronary Collaterals in Chronic Total Occlusion.International journal of cardiology · 2024Article
- Dihydrotestosterone Augments the Angiogenic and Migratory Potential of Human Endothelial Progenitor Cells by an Androgen Receptor-Dependent Mechanism.International journal of molecular sciences · 2024Article
- The association between circulating CD34+CD133+ endothelial progenitor cells and reduced risk of Alzheimer's disease in the Framingham Heart Study.Exploration of medicine · 2024Article
- Meta-regression analysis on the impact of medical therapy on long-term outcome in spontaneous coronary artery dissection.International journal of cardiology. Heart & vasculature · 2023Review
- Mechanism of heart failure after myocardial infarction.The Journal of international medical research · 2023Review
- Latexin regulates sex dimorphism in hematopoiesis via gender-specific differential expression of microRNA 98-3p and thrombospondin 1.Cell reports · 2023Article
- Final five-year results of the REMEDEE Registry: Real-world experience with the dual-therapy COMBO stent.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2021Article
- Pathophysiology of Spontaneous Coronary Artery Dissection Determines Anticoagulation Strategy.Cureus · 2021Review
- Spontaneous splenic rupture due to extramedullary haematopoiesis in a patient with inherited thrombocytopenia.Blood transfusion = Trasfusione del sangue · 2021Article
- Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females.Frontiers in immunology · 2021Article
- Circulating Progenitor Cells in Patients With Coronary Artery Disease and Renal Insufficiency.JACC. Basic to translational science · 2020Article
- Cardiovascular Risk and Resilience Among Black Adults: Rationale and Design of the MECA Study.Journal of the American Heart Association · 2020Article
- Sex differences in cancer mechanisms.Biology of sex differences · 2020Review
- The Effect of Sex Differences on Endothelial Function and Circulating Endothelial Progenitor Cells in Hypertriglyceridemia.Cardiology research and practice · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
backgroundLower levels of circulating progenitor cells (PCs) reflect impaired endogenous regenerative capacity and are associated with aging, vascular disease, and poor outcomes. Whether biologic sex and sex hormones influence PC numbers remains a subject of controversy. We sought to determine sex differences in circulating PCs in both healthy persons and patients with coronary artery disease, and to determine their association with sex hormone levels. METHODS AND
resultsIn 642 participants (mean age 48 years, 69% women, 23% black) free from cardiovascular disease, we measured circulating PC counts as CD45
conclusionsWomen have lower circulating hematopoietic PC levels compared with men. Estrogen levels are modestly associated with PC levels in women. Since PCs are reflective of endogenous regenerative capacity, these findings may at least partly explain the rise in adverse cardiovascular events in women with aging and menopause.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.