Evidence map›Paper›PMID 28974470›Full record

ArticleDiabetes research and clinical practice2017

Diabetes Alert Dogs (DADs): An assessment of accuracy and implications.

Linda A Gonder-Frederick, Jesse H Grabman, Jaclyn A Shepard

Abstract read
In one paragraph

Article in Diabetes research and clinical practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Linda A Gonder-FrederickBehavioral Medicine Center, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: lag3g@virginia.edu.
Jesse H GrabmanBehavioral Medicine Center, University of Virginia, Charlottesville, VA 22908, USA.
Jaclyn A ShepardBehavioral Medicine Center, University of Virginia, Charlottesville, VA 22908, USA.

Funding

Accuracy of Blood Glucose Detection by Diabetes Alert Dogs (DADs)R21DK099697 · NIDDK · UNIVERSITY OF VIRGINIA · PI GONDER-FREDERICK, LINDA ANN · 2013 to 2014
$435k
NIDDK NIH HHS R21 DK099697
6 · The paper itself

Abstract

aimsTo test the accuracy of Diabetes Alert Dogs (DADs) by comparing recorded alerts to continuous glucose monitoring (CGM) device readings during waking and sleeping hours.

methods14 individuals (7 adults with type 1 diabetes and 7 youth with type 1 diabetes/parents) who owned DADs for ≥6 mos wore masked CGM devices over a several-week period while recording DAD alerts electronically and in paper diaries.

resultsDuring waking hours, sensitivity scores across participants were 35.9% for low BG events and 26.2% for high BG events. DAD accuracy was highly variable with 3/14 individual dogs performing statistically higher than chance. Sensitivity scores were lower during sleep hours of the person with diabetes (22.2% for low BG events and 8.4% for high BG events). DAD accuracy during sleeping hours was also highly variable, with 1/11 individual dogs performing statistically better than chance. Rate of change analyses indicated that DADs were responding to absolute BG level, rather than rapid shifts in glucose levels.

conclusionsIn this study the majority of DADs did not demonstrate accurate detection of low and high BG events. However, performance varied greatly across DADs and additional studies are needed to examine factors contributing to this variability. Additionally, more research is needed to investigate the significant gap between the positive experiences and clinical outcomes reported by DAD owners and the mixed research findings on DAD accuracy.

Indexed as

AdultAnimalsBlood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1DogsFemaleHumansHypoglycemiaMaleReproducibility of ResultsYoung AdultBlood GlucoseBlood glucose monitoringCGMDogsObservational studySevere hypoglycemiaType 1

Identifiers

PMID28974470
PMCPMC5723560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.