ArticleNeuroImage2018
Long-term optical imaging of neurovascular coupling in mouse cortex using GCaMP6f and intrinsic hemodynamic signals.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Simultaneous mesoscopic imaging of neural activity and hemodynamics reveals anesthetic modulation of neurovascular responses.Photoacoustics · 2026Article
- Cocaine induced astrocytic activation was associated with its vasoconstricting effects independent of its neuronal effects in the prefrontal cortex.Scientific reports · 2026Article
- A cortex-wide multimodal microscope for simultaneous CaNature communications · 2025Article
- Inhibition of iNOS reduced cerebral vasoconstriction from chronic cocaine and enhanced angiogenesis in the prefrontal cortex.Brain research bulletin · 2025Article
- Review of cocaine-induced brain vascular and cellular function changes measuredNeurophotonics · 2025Review
- Review
- Spatiotemporal relationships between neuronal, metabolic, and hemodynamic signals in the awake and anesthetized mouse brain.Cell reports · 2024Article
- Astrocytes modulate cerebral blood flow and neuronal response to cocaine in prefrontal cortex.Molecular psychiatry · 2024Article
- Functional network disorganization and cognitive decline following fractionated whole-brain radiation in mice.GeroScience · 2024Article
- Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury.Neurophotonics · 2023Review
- FTO-dependent mNature communications · 2023Article
- Cocaine's cerebrovascular vasoconstriction is associated with astrocytic CaCommunications biology · 2022Article
- Cocaine's effects on the reactivity of the medial prefrontal cortex to ventral tegmental area stimulation: optical imaging study in mice.Addiction (Abingdon, England) · 2022Article
- Article
- Early brain activity: Translations between bedside and laboratory.Progress in neurobiology · 2022Review
- Iptakalim improves cerebral microcirculation in mice after ischemic stroke by inhibiting pericyte contraction.Acta pharmacologica Sinica · 2022Article
- Gaining insight into the neural basis of resting-state fMRI signal.NeuroImage · 2022Article
- Development of a Monte Carlo-wave model to simulate time domain diffuse correlation spectroscopy measurements from first principles.Journal of biomedical optics · 2022Article
- Article
- Optical imaging of stimulation-evoked cortical activity using GCaMP6f and jRGECO1a.Quantitative imaging in medicine and surgery · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Cerebral hemodynamics are modulated in response to changes in neuronal activity, a process termed neurovascular coupling (NVC), which can be disrupted by neuropsychiatric diseases (e.g., stroke, Alzheimer's disease). Thus, there is growing interest to image long-term NVC dynamics with high spatiotemporal resolutions. Here, by combining the use of a genetically-encoded calcium indicator with optical techniques, we develop a longitudinal multimodal optical imaging platform (MIP) that enabled time-lapse tracking of NVC over a relatively large field of view in the mouse somatosensory cortex at single cell and single vessel resolutions. Specifically, GCaMP6f was used as marker of neuronal activity, which along with MIP allowed us to simultaneously measure the changes in neuronal [Ca
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