ArticleSensors (Basel, Switzerland)2017
A Novel Fiber Optic Surface Plasmon Resonance Biosensors with Special Boronic Acid Derivative to Detect Glycoprotein.
Article in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Ultrahigh-figure-of-merit refractive-index sensing with grating-coupled magneto-optical hyperbolic metamaterials.Nanoscale advances · 2026Article
- Progress and Trends of Optical Microfiber-Based Biosensors.Biosensors · 2023Review
- A Fiber Bragg Grating Sensor Based on Cladding Mode Resonance for Label-Free Biosensing.Biosensors · 2023Article
- A review of Optical Point-of-Care devices to Estimate the Technology Transfer of These Cutting-Edge Technologies.Biosensors · 2022Review
- Novel Optical Fiber-Based Structures for Plasmonics Sensors.Biosensors · 2022Review
- 2D Material-Based Optical Biosensor: Status and Prospect.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Optical Fiber, Nanomaterial, and THz-Metasurface-Mediated Nano-Biosensors: A Review.Biosensors · 2022Review
- Study on a Plasmonic Tilted Fiber Grating-Based Biosensor for Calmodulin Detection.Biosensors · 2021Article
- Nanometer-Sized Boron Loaded Liposomes Containing FeMaterials (Basel, Switzerland) · 2021Article
- High Sensitivity Humidity Detection Based on Functional GO/MWCNTs Hybrid Nano-Materials Coated Titled Fiber Bragg Grating.Nanomaterials (Basel, Switzerland) · 2021Article
- Plasmonic and Hybrid Whispering Gallery Mode-Based Biosensors: Literature Review.JMIR biomedical engineering · 2021Review
- Review
- Plasmonic Optical Fiber-Grating Immunosensing: A Review.Sensors (Basel, Switzerland) · 2017Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We proposed and demonstrated a novel tilted fiber Bragg grating (TFBG)-based surface plasmon resonance (SPR) label-free biosensor via a special boronic acid derivative to detect glycoprotein with high sensitivity and selectivity. TFBG, as an effective sensing element for optical sensing in near-infrared wavelengths, possess the unique capability of easily exciting the SPR effect on fiber surface which coated with a nano-scale metal layer. SPR properties can be accurately detected by measuring the variation of transmitted spectra at optical communication wavelengths. In our experiment, a 10° TFBG coated with a 50 nm gold film was manufactured to stimulate SPR on a sensor surface. To detect glycoprotein selectively, the sensor was immobilized using designed phenylboronic acid as the recognition molecule, which can covalently bond with 1,2- or 1,3-diols to form five- or six-membered cyclic complexes for attaching diol-containing biomolecules and proteins. The phenylboronic acid was synthetized with long alkyl groups offering more flexible space, which was able to improve the capability of binding glycoprotein. The proposed TFBG-SPR sensors exhibit good selectivity and repeatability with a protein concentration sensitivity up to 2.867 dB/ (mg/mL) and a limit of detection (LOD) of 15.56 nM.
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