Evidence map›Paper›PMID 28973946›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Host-derived fatty acids activate type VII secretion in

Michael S Lopez, Irene S Tan, Donghong Yan, Jing Kang, Mark McCreary, Zora Modrusan, Cary D Austin, Min Xu, Eric J Brown

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
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  5. Host-driven remodelling of theMicrobiology (Reading, England) · 2026
    Review
  6. Article
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  8. Article
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  12. Review
  13. Bacterial acquisition of host fatty acids has far-reaching implications on virulence.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael S LopezDepartment of Infectious Disease, Genentech Inc., South San Francisco, CA 94080; micstelop@gmail.com brown.eric@gene.com.
Irene S TanDepartment of Infectious Disease, Genentech Inc., South San Francisco, CA 94080.
Donghong YanDepartment of Translational Immunology, Genentech Inc., South San Francisco, CA 94080.
Jing KangDepartment of Translational Immunology, Genentech Inc., South San Francisco, CA 94080.
Mark McCrearyDepartment of Bioinformatics, Genentech Inc., South San Francisco, CA 94080.
Zora ModrusanDepartment of Molecular Biology, Genentech Inc., South San Francisco, CA 94080.
Cary D AustinDepartment of Research Pathology, Genentech Inc., South San Francisco, CA 94080.
Min XuDepartment of Translational Immunology, Genentech Inc., South San Francisco, CA 94080.
Eric J BrownDepartment of Infectious Disease, Genentech Inc., South San Francisco, CA 94080; micstelop@gmail.com brown.eric@gene.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The type VII secretion system (T7SS) of

Indexed as

Host-Pathogen InteractionsAnimalsHumansLinoleic AcidMiceStaphylococcus aureusType VII Secretion SystemsVirulence FactorsLinoleic AcidType VII Secretion SystemsVirulence Factorsfatty acidsStaphylococcus aureustype VII secretionvirulence

Identifiers

PMID28973946
PMCPMC5651732
OpenAlexW2762519406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.