Evidence map›Paper›PMID 28973908›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Substance P induces plasticity and synaptic tagging/capture in rat hippocampal area CA2.

Ananya Dasgupta, Nimmi Baby, Kumar Krishna, Muhammad Hakim, Yuk Peng Wong, Thomas Behnisch, Tuck Wah Soong, Sreedharan Sajikumar

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 66 citations in OpenAlex.

  1. Caffeine reverses sleep deprivation-induced synaptic and social memory deficits via adenosine receptor modulation in the male mouse hippocampal CA2 region.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  7. Developmental CA2 perineuronal net reduction restores social memory inbioRxiv : the preprint server for biology · 2025
    Article
  8. Hippocampal CA2 to CA1: A metaplastic switch for memory encoding.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
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  11. Review
  12. Synapses tagged, memories kept: synaptic tagging and capture hypothesis in brain health and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  13. Article
  14. E3 Ubiquitin LigaseInternational journal of molecular sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ananya DasguptaDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597.
Nimmi BabyDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597.
Kumar KrishnaDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597.
Muhammad HakimDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597.
Yuk Peng WongDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597.
Thomas BehnischThe Institutes of Brain Science, The State Key Laboratory of Medical Neurobiology, The Collaborative Innovation Centre for Brain Science, Fudan University, Shanghai 200032, China.
Tuck Wah SoongDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597.
Sreedharan SajikumarDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597; phssks@nus.edu.sg.ORCID 0000-0002-5761-8982
National University of Singapore · SGFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hippocampal area

Indexed as

AnimalsCA2 Region, HippocampalCells, CulturedElectric StimulationLong-Term PotentiationNeuronal PlasticityNeuronsRatsSubstance PSynapsesSynaptic TransmissionSubstance PCA2 regionlong-term potentiationsocial memorySubstance Psynaptic tagging

Identifiers

PMID28973908
PMCPMC5642719
OpenAlexW2761429611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.