Evidence map›Paper›PMID 28973867›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

A gut feeling about multiple sclerosis.

Francisco J Quintana, Marco Prinz

Registry-linked trialAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03975413 (Single-Arm, Non-Randomized, Time Series, Single-Subject Study), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03975413 completednot on this mapstarted 2018, after this paper: background citation

Single-Arm, Non-Randomized, Time Series, Single-Subject Study: Fecal Microbiota Transplantation (FMT) in Multiple Sclerosis

TypeobservationalSponsorRush University Medical CenterRan2018 to 2020Enrolled1ConditionsMultiple Sclerosis, Relapsing-RemittingArmsFecal Microbiota Transplantation (FMT)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. The aryl hydrocarbon receptor and the gut-brain axis.Cellular & molecular immunology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Francisco J QuintanaAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115; fquintana@rics.bwh.harvard.edu.
Marco PrinzBIOSS Centre for Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany.

Funding

Role of AHR in Dendritic Cells in the Control of the CNS AutoimmunityR01ES025530 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI Francisco J. Quintana · 2016 to 2026
$3.7M
Regulation of CNS AutoimmunityR01AI126880 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI QUINTANA, FRANCISCO J. · 2017 to 2021
$2.1M
Role of aryl hydrocarbon receptor in IL-10 producing Tr1 regulatory cellsR01AI093903 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI QUINTANA, FRANCISCO J. · 2011 to 2015
$1.9M
Role of aryl hydrocarbon receptor in IL-10 producing Tr1 regulatory cellsR56AI093903 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI QUINTANA, FRANCISCO J. · 2016 to 2016
$413k
Role and Therapeutic Value of AHR in Inflammatory Macrophages during GBMR21NS087867 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI QUINTANA, FRANCISCO J., WEINER, HOWARD L · 2014 to 2015
$259k
NIAID NIH HHS R01 AI093903NIAID NIH HHS R01 AI126880NIAID NIH HHS R56 AI093903NIEHS NIH HHS R01 ES025530NINDS NIH HHS R21 NS087867
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal MicrobiomeMultiple SclerosisEmotionsHumans

Identifiers

PMID28973867
PMCPMC5635933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.