Evidence map›Paper›PMID 28973856›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Rewiring a Rab regulatory network reveals a possible inhibitory role for the vesicle tether, Uso1.

Hua Yuan, Saralin Davis, Susan Ferro-Novick, Peter Novick

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Arf1 orchestrates Rab GTPase conversion at theMolecular biology of the cell · 2021
    Article
  6. Article
  7. Newer Methods Drive Recent Insights into Rab GTPase Biology: An Overview.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hua YuanDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Saralin DavisDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Susan Ferro-NovickDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Peter NovickDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093 pnovick@ucsd.edu.
University of California, San Diego · US

Funding

GENETICS OF SECRETION IN YEASTR01GM035370 · NIGMS · YALE UNIVERSITY · PI PETER Jay NOVICK · 1985 to 2026
$7.0M
Coordination of membrane traffic through rab GEF and GAP cascadesR01GM082861 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NOVICK, PETER JAY · 2008 to 2020
$4.4M
The role of a CK1 kinase in membrane trafficR01GM114111 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FERRO-NOVICK, SUSAN · 2015 to 2018
$1.5M
The contribution of the secretory pathway to macroautophagyR01GM115422 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FERRO-NOVICK, SUSAN · 2016 to 2018
$1.1M
NIGMS NIH HHS R01 GM035370NIGMS NIH HHS R01 GM082861NIGMS NIH HHS R01 GM114111NIGMS NIH HHS R01 GM115422
6 · The paper itself

Abstract

Ypt1 and Sec4 are essential Rab GTPases that control the early and late stages of the yeast secretory pathway, respectively. A chimera consisting of Ypt1 with the switch I domain of Sec4, Ypt1-SW1

Indexed as

Cell MembraneEndoplasmic ReticulumGolgi ApparatusGuanine Nucleotide Exchange FactorsProtein Bindingrab GTP-Binding ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVesicular Transport ProteinsGuanine Nucleotide Exchange Factorsrab GTP-Binding ProteinsSaccharomyces cerevisiae ProteinsUSO1 protein, S cerevisiaeVesicular Transport Proteinsmembrane trafficRab GTPasevesicle tether

Identifiers

PMID28973856
PMCPMC5642711
OpenAlexW2763571393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.