ArticleBritish journal of cancer2018
Maternal diabetes and risk of childhood acute lymphoblastic leukaemia in the offspring.
Article in British journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Maternal Body Mass Index, Diabetes, and Gestational Weight Gain and Risk for Pediatric Cancer in Offspring: A Systematic Review and Meta-Analysis.JNCI cancer spectrum · 2022Pooled it
- Maternal Medication Use and Childhood Cancer in Offspring-Systematic Review and Considerations for Researchers.American journal of epidemiology · 2021Pooled it
- Maternal diabetes and risk of childhood malignancies in the offspring: a systematic review and meta-analysis of observational studies.Acta diabetologica · 2021Pooled it
- Mode of delivery and the risk of lymphoblastic leukemia during childhood-A Swedish population-based cohort study.International journal of cancer · 2025Article
- Exclusive Breastfeeding Duration and Risk of Childhood Cancers.JAMA network open · 2024Article
- The Relationship Between Gestational Diabetes and the Risk of Cancer: A Systematic Review.Cureus · 2024Review
- Maternal diet in pregnancy and acute leukemia in infants: a case-control study in Mexico City.Frontiers in oncology · 2023Article
- Maternal diabetes and childhood cancer risks in offspring: two population-based studies.British journal of cancer · 2022Article
- Article
- Maternal autoimmune disease is not associated with cancer in the offspring.Acta paediatrica (Oslo, Norway : 1992) · 2021Article
- Cancer Progress and Priorities: Childhood Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaternal diabetes may be linked to childhood acute lymphoblastic leukaemia (ALL) in the offspring.
methodsWe assessed the association between maternal pregestational or gestational diabetes and offspring risk of childhood ALL in a register-based study, including all singletons born in Denmark during 1996-2015 (n=1 187 482).
resultsAdjusted hazard ratios of childhood ALL were 2.91 (95% confidence interval (CI): 1.30-6.51) for maternal pregestational diabetes and 1.75 (95% CI: 1.02-2.98) for maternal gestational diabetes. Paternal diabetes did not alter offspring ALL risk, and we found no association between offspring ALL and later maternal risk of diabetes.
conclusionsRegardless that absolute ALL risk among offspring of women with diabetes remains low, our findings suggest that characteristics of the diabetic intrauterine environment promote ALL development. This offers a setting for future research into the biological mechanisms underlying childhood ALL.
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