ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2017
The rate of lactate production from glucose in hearts is not altered by per-deuteration of glucose.
Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Advancing Deuterium MRI to Track Human Cerebral Glucose Metabolism at 7 T: A Comparison of Glucose-dNMR in biomedicine · 2025Article
- Directly Bound Deuterons Increase X-Nuclei Hyperpolarization using Dynamic Nuclear Polarization.Chemphyschem : a European journal of chemical physics and physical chemistry · 2023Article
- Measuring NQO1 Bioactivation Using [Cancers · 2021Article
- Deuterium metabolic imaging - Back to the future.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021Review
- Characterization of Kinetic Isotope Effects and Label Loss in Deuterium-Based Isotopic Labeling Studies.ACS chemical neuroscience · 2021Article
- HDO production from [Scientific reports · 2020Article
- Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis.Journal of lipid research · 2019Article
- Probing carbohydrate metabolism using hyperpolarizedNMR in biomedicine · 2019Review
- Effects of deuteration on transamination and oxidation of hyperpolarizedJournal of magnetic resonance (San Diego, Calif. : 1997) · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
This study was designed to determine whether perdeuterated glucose experiences a kinetic isotope effect (KIE) as glucose passes through glycolysis and is further oxidized in the tricarboxylic acid (TCA) cycle. Metabolism of deuterated glucose was investigated in two groups of perfused rat hearts. The control group was supplied with a 1:1 mixture of [U-
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.