Evidence map›Paper›PMID 28972744›Full record

ArticleChemical research in toxicology2017

Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ.

Oliver P Yockey, Vikash Jha, Pratibha P Ghodke, Tianzuo Xu, Wenyan Xu, Hong Ling, P I Pradeepkumar, Linlin Zhao

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. DNA polymerases η and κ bypass NThe Journal of biological chemistry · 2021
    Article
  4. Review
  5. Mammalian DNA Polymerase Kappa Activity and Specificity.Molecules (Basel, Switzerland) · 2019
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Oliver P Yockey
Vikash JhaDepartment of Biochemistry, Schulich School of Medicine & Dentistry, University of Western Ontario , London, Ontario N6A 5C1, Canada.
Pratibha P GhodkeDepartment of Chemistry, Indian Institute of Technology Bombay , Mumbai 400076, India.
Tianzuo Xu
Wenyan Xu
Hong LingDepartment of Biochemistry, Schulich School of Medicine & Dentistry, University of Western Ontario , London, Ontario N6A 5C1, Canada.
P I PradeepkumarDepartment of Chemistry, Indian Institute of Technology Bombay , Mumbai 400076, India.ORCID 0000-0001-9104-3708
Indian Institute of Technology Bombay · INWestern University · CA

Funding

Novel functions of PrimPol in ribonucleotide-induced genome instabilityR15GM117522 · NIGMS · CENTRAL MICHIGAN UNIVERSITY · PI ZHAO, LINLIN · 2016 to 2016
$432k
CIHR MOP-67128NIGMS NIH HHS R15 GM117522
6 · The paper itself

Abstract

DNA damage impinges on genetic information flow and has significant implications in human disease and aging. Lucidin-3-O-primeveroside (LuP) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. LuP can be metabolically converted to genotoxic compound lucidin, which subsequently forms lucidin-specific N

Indexed as

DNA DamageDNA ReplicationAnthraquinonesCarcinogensCrystallography, X-RayDNA AdductsDNA-Directed DNA PolymeraseHumansModels, MolecularY-Family DNA PolymerasesAnthraquinonesCarcinogensDNA AdductsDNA-Directed DNA PolymeraselucidinPOLK protein, humanY-Family DNA Polymerases

Identifiers

PMID28972744
PMCPMC5696069
OpenAlexW2762459784

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.