Evidence map›Paper›PMID 28972188›Full record

ReviewThe Journal of biological chemistry2017

Understanding DNA replication by the bacteriophage T4 replisome.

Stephen J Benkovic, Michelle M Spiering

Open access · hybridAbstract readComparative StudyReview
In one paragraph

Review in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Introduction.Advances in experimental medicine and biology · 2026
    Article
  3. Article
  4. Review
  5. Comprehensive Approaches to CombattingAntibiotics (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephen J BenkovicFrom the Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802 sjb1@psu.edu.ORCID 0000-0003-3680-3481
Michelle M SpieringFrom the Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802.
Pennsylvania State University · US

Funding

PHOSPHATE ACTIVATION MECHANISMSR01GM013306 · NIGMS · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI BENKOVIC, STEPHEN J · 1985 to 2022
$10.0M
NIGMS NIH HHS R01 GM013306
6 · The paper itself

Abstract

The T4 replisome has provided a unique opportunity to investigate the intricacies of DNA replication. We present a comprehensive review of this system focusing on the following: its 8-protein composition, their individual and synergistic activities, and assembly

Indexed as

DNA ReplicationModels, MolecularBacteriophage T4Bacteriophage T7Carbon-Nitrogen LigasesDNA-Directed DNA PolymeraseEscherichia coliEscherichia coli ProteinsMultienzyme ComplexesProtein MultimerizationReplisomesSpecies SpecificityViral ProteinsCarbon-Nitrogen LigasesDNA-Directed DNA PolymeraseEscherichia coli Proteinsholocarboxylase synthetasesMultienzyme ComplexesReplisomesViral ProteinsbacteriophageDNA-binding proteinDNA helicaseDNA polymeraseDNA primaseDNA replication

Identifiers

PMID28972188
PMCPMC5682956
OpenAlexW2762768319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.