Evidence map›Paper›PMID 28972185›Full record

ArticleThe Journal of biological chemistry2017

Calmodulin regulates Ca

Jean Chemin, Valentina Taiakina, Arnaud Monteil, Michael Piazza, Wendy Guan, Robert F Stephens, Ashraf Kitmitto, Zhiping P Pang, Annette C Dolphin, Edward Perez-Reyes and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. The T-type calcium channelosome.Pflugers Archiv : European journal of physiology · 2024
    Review
  6. Article
  7. Calmodulin Mutations in Human Disease.Channels (Austin, Tex.) · 2023
    Review
  8. Review
  9. Article
  10. CaHandbook of experimental pharmacology · 2023
    Article
  11. Review
  12. Investigation ofFrontiers in molecular neuroscience · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Conserved biophysical features of the CaThe Journal of biological chemistry · 2020
    Article
  17. Article
  18. Neuronal Cav3 channelopathies: recent progress and perspectives.Pflugers Archiv : European journal of physiology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Jean CheminInstitut de Génomique Fonctionnelle, CNRS, INSERM, Université de Montpellier, Montpellier F-34094, France.
Valentina TaiakinaDepartments of Chemistry, Waterloo, Ontario N2L 3G1, Canada.
Arnaud MonteilInstitut de Génomique Fonctionnelle, CNRS, INSERM, Université de Montpellier, Montpellier F-34094, France.
Michael PiazzaDepartments of Chemistry, Waterloo, Ontario N2L 3G1, Canada.
Wendy GuanBiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
Robert F StephensBiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
Ashraf KitmittoDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9NT, United Kingdom.
Zhiping P PangDepartment of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901.
Annette C DolphinDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom.
Edward Perez-ReyesDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia 22908.
Thorsten DieckmannDepartments of Chemistry, Waterloo, Ontario N2L 3G1, Canada.
Joseph Guy GuillemetteDepartments of Chemistry, Waterloo, Ontario N2L 3G1, Canada.
J David SpaffordBiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada. Electronic address: spafford@uwaterloo.ca.
University of Waterloo · CACentre National de la Recherche Scientifique · FRRutgers, The State University of New Jersey · USUniversity College London · GBUniversity of Manchester · GBUniversity of Virginia · US

Funding

Mechanisms by which T-type calcium channels increase seizure susceptibilityR01NS067456 · NINDS · UNIVERSITY OF VIRGINIA · PI PEREZ-REYES, EDWARD · 2009 to 2010
$770k
British Heart FoundationMedical Research Council G0801756Medical Research Council G0901758NINDS NIH HHS R01 NS067456Wellcome Trust
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

Ion Channel GatingAnimalsBinding SitesBrainCalciumCalcium Channels, T-TypeCalmodulinCaveolin 3HeartHumansInvertebratesPeriodicityCACNA1G protein, humanCACNA1H protein, humanCACNA1I protein, humanCalciumCalcium Channels, T-TypeCalmodulinCAV3 protein, humanCaveolin 3calcium channelcircular dichroism (CD)cryo-electron microscopygatingisothermal titration calorimetry (ITC)nuclear magnetic resonance (NMR)patch clampshort hairpin RNA (shRNA)

Identifiers

PMID28972185
PMCPMC5723990
OpenAlexW2761365854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.