Evidence map›Paper›PMID 28972145›Full record

ArticleThe Journal of biological chemistry2017

Structural analyses of the MazEF4 toxin-antitoxin pair in

Do-Hwan Ahn, Ki-Young Lee, Sang Jae Lee, Sung Jean Park, Hye-Jin Yoon, Soon-Jong Kim, Bong-Jin Lee

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Long Dynamic β1-β2 Loops inInternational journal of molecular sciences · 2024
    Article
  3. Identification of Genes Encoded Toxin-Antitoxin System inInfectious disorders drug targets · 2024
    Article
  4. Article
  5. Potential Efficacy ofMolecules (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Article
  8. Localization ofFrontiers in microbiology · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. mRNA InterferaseToxins · 2020
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Do-Hwan AhnFrom the Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Seoul 151-742.
Ki-Young LeeFrom the Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Seoul 151-742.
Sang Jae LeeFrom the Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Seoul 151-742.
Sung Jean Parkthe College of Pharmacy, Gachon University, 534-2 Yeonsu-dong, Yeonsu-gu, Incheon.
Hye-Jin Yoonthe Department of Biophysics and Chemical Biology, College of Natural Sciences, Seoul National University, Seoul 151-742, and.
Soon-Jong Kimthe Department of Chemistry, Mokpo National University, Chonnam 534-729, Republic of Korea.
Bong-Jin LeeFrom the Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Seoul 151-742, lbj@nmr.snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bacterial toxin-antitoxin MazEF system in the tuberculosis (TB)-causing bacterium

Indexed as

Amino Acid SequenceAntitoxinsBacterial ProteinsBacterial ToxinsCrystallography, X-RayDrug DiscoveryEndoribonucleasesHumansModels, MolecularMycobacterium tuberculosisPeptidesProtein ConformationProtein MultimerizationQuorum SensingSequence AlignmentTuberculosisAntitoxinsBacterial ProteinsBacterial ToxinsEndoribonucleasesMazE4 protein, Mycobacterium tuberculosisMazF protein, Mycobacterium tuberculosisPeptidesextracellular death factorMazEF systemMycobacterium tuberculosisnuclear magnetic resonance (NMR)protein structurequorum sensingtoxin-antitoxin systemX-ray crystallography

Identifiers

PMID28972145
PMCPMC5704469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.