Evidence map›Paper›PMID 28972139›Full record

ArticleThe Journal of biological chemistry2017

Interphotoreceptor retinoid-binding protein removes all-

Chunhe Chen, Leopold Adler, Patrice Goletz, Federico Gonzalez-Fernandez, Debra A Thompson, Yiannis Koutalos

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Advances and therapeutic opportunities in visual cycle modulation.Progress in retinal and eye research · 2025
    Review
  6. Article
  7. The First Steps of the Visual Cycle in Human Rod and Cone Photoreceptors.Investigative ophthalmology & visual science · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Photooxidation mediated by 11-Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2020
    Article
  14. Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  15. Review
  16. Article
  17. Review
  18. Structural biology of 11-The Biochemical journal · 2018
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chunhe ChenFrom the Departments of Ophthalmology and Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425.
Leopold AdlerFrom the Departments of Ophthalmology and Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425.
Patrice GoletzFrom the Departments of Ophthalmology and Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425.
Federico Gonzalez-Fernandezthe Departments of Ophthalmology and Pathology, University of Mississippi and G. V. (Sonny) Montgomery Veterans Affairs Medical Centers, Jackson, Mississippi 39216, and.
Debra A Thompsonthe Departments of Ophthalmology and Visual Sciences, and Biological Chemistry, University of Michigan School of Medicine, Ann Arbor, Michigan 48105.
Yiannis KoutalosFrom the Departments of Ophthalmology and Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, koutalo@musc.edu.
Medical University of South Carolina · USUniversity of Michigan · USUniversity of Mississippi · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Antonetti · 1987 to 2026
$17.6M
Transport Processes in PhotoreceptorsR01EY014850 · NEI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KOUTALOS, YIANNIS · 2004 to 2022
$5.3M
IRBP--STRUCTURE/FUNCTIONR01EY009412 · NEI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GHOSH, DEBASHIS, GONZALEZ-FERNANDEZ, FEDERICO · 1999 to 2011
$3.0M
MUSC FACIL EXPANSION &RENOV: SLE C06RR015455 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RAYMOND, JOHN R · 2002 to 2002
$2.0M
NCATS NIH HHS UL1 TR001412NCRR NIH HHS C06 RR015455NEI NIH HHS P30 EY007003NEI NIH HHS R01 EY009412NEI NIH HHS R01 EY014850
6 · The paper itself

Abstract

Interphotoreceptor retinoid-binding protein (IRBP) is a specialized lipophilic carrier that binds the all-

Indexed as

AnimalsCattleEye ProteinsLightLipofuscinMiceMice, KnockoutRetinaldehydeRetinol-Binding ProteinsRetinol-Binding Proteins, InterstitialRod Cell Outer SegmentVitamin AEye ProteinsLipofuscinRetinaldehydeRetinol-Binding ProteinsRetinol-Binding Proteins, InterstitialVitamin Afluorescencephotoreceptorretinaretinoid-binding proteinretinol

Identifiers

PMID28972139
PMCPMC5702674
OpenAlexW2758589020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.