ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Dynamic Trial-by-Trial Recoding of Task-Set Representations in the Frontoparietal Cortex Mediates Behavioral Flexibility.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta-analysis of cognitive flexibility in aging: Perspective from functional network and lateralization.Human brain mapping · 2024Pooled it
- Task-specific theta enhancement and domain-general alpha/beta suppression as oscillatory signatures of cognitive flexibility.Communications psychology · 2026Article
- Hierarchical Reconfiguration of Neurocognitive Task Set Representations Mediates Cognitive Flexibility.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Steering through task uncertainty: Evidence for activation modulation over dynamic binding.Psychonomic bulletin & review · 2026Article
- Hierarchical Reconfiguration of Neurocognitive Task Set Representations Mediates Cognitive Flexibility.bioRxiv : the preprint server for biology · 2026Article
- Convergent neural dynamical systems for task control in artificial networks and human brains.bioRxiv : the preprint server for biology · 2025Article
- Task-Switch Related Reductions in Neural Distinctiveness in Children and Adults: Commonalities and Differences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Frontiers in neuro-rehabilitation: neural basis of cognitive contributions to movement across neurological populations.Frontiers in neurology · 2025Review
- Contextual control demands determine whether stability and flexibility trade off against each other.Attention, perception & psychophysics · 2024Article
- Learning Cognitive Flexibility: Neural Substrates of Adapting Switch-Readiness to Time-varying Demands.Journal of cognitive neuroscience · 2024Article
- Attention switching through text dissimilarity: a cognition research on fragmented reading behavior.Frontiers in human neuroscience · 2024Article
- The Involvement of the Multiple Demand and Default Mode Networks in a Trial-by-Trial Cognitive Control.Brain sciences · 2023Article
- Subspace partitioning in the human prefrontal cortex resolves cognitive interference.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Interaction Between Memory Load and Experimental Design on Brain Connectivity and Network Topology.Neuroscience bulletin · 2023Article
- Sensory experience modulates the reorganization of auditory regions for executive processing.Brain : a journal of neurology · 2022Article
- Neural Dynamics of Context-sensitive Adjustments in Cognitive Flexibility.Journal of cognitive neuroscience · 2022Article
- Task switching involves working memory: Evidence from neural representation.Frontiers in psychology · 2022Article
- Understanding cognitive control in aging: A brain network perspective.Frontiers in aging neuroscience · 2022Review
- Neural Coding of Cognitive Control: The Representational Similarity Analysis Approach.Trends in cognitive sciences · 2021Review
- Task-evoked pupillary responses track effort exertion: Evidence from task-switching.Cognitive, affective & behavioral neuroscience · 2021Article
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4 authors.
Funding
Abstract
Cognitive flexibility forms the core of the extraordinary ability of humans to adapt, but the precise neural mechanisms underlying our ability to nimbly shift between task sets remain poorly understood. Recent functional magnetic resonance imaging (fMRI) studies employing multivoxel pattern analysis (MVPA) have shown that a currently relevant task set can be decoded from activity patterns in the frontoparietal cortex, but whether these regions support the dynamic transformation of task sets from trial to trial is not clear. Here, we combined a cued task-switching protocol with human (both sexes) fMRI, and harnessed representational similarity analysis (RSA) to facilitate a novel assessment of trial-by-trial changes in neural task-set representations. We first used MVPA to define task-sensitive frontoparietal and visual regions and found that neural task-set representations on switch trials are less stably encoded than on repeat trials. We then exploited RSA to show that the neural representational pattern dissimilarity across consecutive trials is greater for switch trials than for repeat trials, and that the degree of this pattern dissimilarity predicts behavior. Moreover, the overall neural pattern of representational dissimilarities followed from the assumption that repeating sets, compared with switching sets, results in stronger neural task representations. Finally, when moving from cue to target phase within a trial, pattern dissimilarities tracked the transformation from previous-trial task representations to the currently relevant set. These results provide neural evidence for the longstanding assumptions of an effortful task-set reconfiguration process hampered by task-set inertia, and they demonstrate that frontoparietal and stimulus processing regions support "dynamic adaptive coding," flexibly representing changing task sets in a trial-by-trial fashion.
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