Evidence map›Paper›PMID 28972103›Full record

ArticleThe Journal of cell biology2017

TORC1 signaling exerts spatial control over microtubule dynamics by promoting nuclear export of Stu2.

Babet van der Vaart, Josef Fischböck, Christine Mieck, Peter Pichler, Karl Mechtler, René H Medema, Stefan Westermann

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. TOR Complex 1: Orchestrating Nutrient Signaling and Cell Cycle Progression.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Babet van der VaartResearch Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria b.vd.vaart@nki.nl.
Josef FischböckResearch Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.
Christine MieckResearch Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.ORCID 0000-0003-1919-7416
Peter PichlerResearch Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.ORCID 0000-0001-8340-0197
Karl MechtlerResearch Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.ORCID 0000-0002-3392-9946
René H MedemaDivision of Cell Biology, The Netherlands Cancer Institute, Amsterdam, Netherlands.
Stefan WestermannResearch Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria stefan.westermann@uni-due.de.ORCID 0000-0001-6921-9113
Research Institute of Molecular Pathology · ATThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The target of rapamycin complex 1 (TORC1) is a highly conserved multiprotein complex that functions in many cellular processes, including cell growth and cell cycle progression. In this study, we define a novel role for TORC1 as a critical regulator of nuclear microtubule (MT) dynamics in the budding yeast

Indexed as

Active Transport, Cell NucleusCell NucleusInterphaseKineticsMating FactorMembrane ProteinsMicrotubule-Associated ProteinsMicrotubulesMitosisPhosphorylationProtein Serine-Threonine KinasesRibosomal Protein S6 Kinases, 70-kDaSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionTranscription Factorsalpha-factor (Saccharomyces cerevisiae)Bik1 protein, S cerevisiaeKog1 protein, S cerevisiaeMating FactorMembrane ProteinsMicrotubule-Associated ProteinsProtein Serine-Threonine Kinasesribosomal protein S6 kinase, 70kD, polypeptide 1Ribosomal Protein S6 Kinases, 70-kDaSaccharomyces cerevisiae ProteinsSCH9 protein, S cerevisiaeSTU2 protein, S cerevisiaeTORC1 protein complex, S cerevisiaeTranscription Factors

Identifiers

PMID28972103
PMCPMC5674874
OpenAlexW2758281806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.