ArticleCancer research2017
SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells.
Abstract read
In one paragraph
Article in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- The human THRB thyroid hormone receptor gene and the puzzle of retinal disease phenotypes.Developmental biology · 2026Review
- Thyroid hormone signaling in ocular development and diseases.Biological research · 2025Review
- Differentiation versus dysfunction: thyroid hormone, deiodinases and retinal photoreceptors.European thyroid journal · 2025Review
- Loss of EMI1 compromises chromosome stability and is associated with cellular transformation in colonic epithelial cell contexts.British journal of cancer · 2024Article
- Retinoblastoma: A review of the molecular basis of tumor development and its clinical correlation in shaping future targeted treatment strategies.Indian journal of ophthalmology · 2023Review
- The role of Fbxo5 in the development of human malignant tumors.American journal of cancer research · 2022Review
- Retinoblastoma: Etiology, Modeling, and Treatment.Cancers · 2020Review
- A novel thyroid hormone receptor isoform, TRβ2-46, promotes SKP2 expression and retinoblastoma cell proliferation.The Journal of biological chemistry · 2019Article
- A three-dimensional organoid model recapitulates tumorigenic aspects and drug responses of advanced human retinoblastoma.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 1 institution in 1 country.
Xiaoliang L XuDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Zhengke LiThe Vision Center, Department of Surgery and The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California.
Aihong LiuDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.
Xianqun FanDepartment of Ophthalmology, Ninth People's Hospital, Shanghai Jiaotong University, Shanghai, P.R. China.
Dan-Ning HuNew York Eye and Ear Infirmary, New York Medical College, New York, New York.
Dong-Lai QiThe Vision Center, Department of Surgery and The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California.
David W ChittyDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Renbing JiaDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Jianping QuiDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Justin Q WangDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Jake SharafDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Jun ZouDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Rebecca WeissDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Hongyan HuangDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Walter J JosephDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Lily NgNational Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland.
Richard RosenNew York Eye and Ear Infirmary, New York Medical College, New York, New York.
Binghui ShenDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, California.
Mark W ReidThe Vision Center, Department of Surgery and The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California.
Douglas ForrestNational Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland.
David H AbramsonDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.
Samuel SingerDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.
David CobrinikThe Vision Center, Department of Surgery and The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California. Jhanwars@mskcc.org dcobrinik@chla.usc.edu.
Suresh C JhanwarDepartment of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York. Jhanwars@mskcc.org dcobrinik@chla.usc.edu.
Memorial Sloan Kettering Cancer Center · US
Funding
USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4MFunctions of thyroid hormone in retinal developmentZIADK047036 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI FORREST, DOUGLAS · 2009 to 2025
$11.2MSPORE in Soft Tissue SarcomaP50CA140146 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LADANYI, MARC · 2010 to 2014
$11.1MRole of Nucleases in RNA Primer Removal and MutagenesisR01CA085344 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI SHEN, BINGHUI · 1999 to 2024
$7.7MSuccessive responses to oncogenic aberrations in retinoblastoma genesis.R01CA137124 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI David Cobrinik · 2011 to 2026
$6.3MIntramural NIH HHS ZIA DK047036NCI NIH HHS P30 CA014089NCI NIH HHS P50 CA140146NCI NIH HHS R01 CA085344NCI NIH HHS R01 CA137124
Abstract
Germline
Indexed as
AnimalsCell ProliferationCell Transformation, NeoplasticGerm-Line MutationHCT116 CellsHEK293 CellsHumansMiceMice, KnockoutRetinoblastoma ProteinS-Phase Kinase-Associated ProteinsThyroid Hormone Receptors betaTranscriptional ActivationTumor Cells, CulturedRetinoblastoma ProteinS-Phase Kinase-Associated ProteinsThyroid Hormone Receptors beta
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.