Evidence map›Paper›PMID 28972039›Full record

Trial reportClinical cancer research : an official journal of the American Association for Cancer Research2017

A Randomized Phase II Trial of Adjuvant Galinpepimut-S, WT-1 Analogue Peptide Vaccine, After Multimodality Therapy for Patients with Malignant Pleural Mesothelioma.

Marjorie G Zauderer, Anne S Tsao, Tao Dao, Katherine Panageas, W Victoria Lai, Andreas Rimner, Valerie W Rusch, Prasad S Adusumilli, Michelle S Ginsberg, Daniel Gomez and 4 more

Registry-linked trialAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01265433 (Randomized Phase II Study of Adjuvant WT-1 Analog Peptide Vaccine in Patients With Malignant Pleural Mesothelioma), which is not on this map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01265433 phase2completednot on this map

Randomized Phase II Study of Adjuvant WT-1 Analog Peptide Vaccine in Patients With Malignant Pleural Mesothelioma (MPM) After Completion of Combined Modality Therapy

TypeinterventionalSponsorSellas Life Sciences GroupRan2010 to 2017Enrolled41ConditionsMalignant Pleural MesotheliomaArmsGalinpepimut-S + Montanide + GM-CSF, Montanide + GM-CSF
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
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  19. Review
  20. Immunotherapy approaches for malignant pleural mesothelioma.Nature reviews. Clinical oncology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Marjorie G ZaudererDivision of Solid Tumor Oncology, Department of Medicine, Thoracic Oncology Service Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York. zauderem@mskcc.org.
Anne S TsaoDivision of Cancer Medicine, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Tao DaoMolecular Pharmacology Program, Sloan Kettering Institute, New York, New York.
Katherine PanageasDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
W Victoria LaiDivision of Solid Tumor Oncology, Department of Medicine, Thoracic Oncology Service Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York.
Andreas RimnerDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Valerie W RuschDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Prasad S AdusumilliDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Michelle S GinsbergDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Daniel GomezDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
David RiceDepartment of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Reza MehranDepartment of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
David A ScheinbergMolecular Pharmacology Program, Sloan Kettering Institute, New York, New York.
Lee M KrugDivision of Solid Tumor Oncology, Department of Medicine, Thoracic Oncology Service Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York.
Memorial Sloan Kettering Cancer Center · USThe University of Texas MD Anderson Cancer Center · USKettering University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
T LYMPHOCYTE SUBSET FUNCTION POST-TRANSPLANTATIONP01CA023766 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI PAMER, ERIC G. · 1985 to 2023
$59.0M
RECOMBINANT ANTICD33 ANTIBODY FOR AMLR01CA055349 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SCHEINBERG, DAVID A · 1991 to 2020
$6.8M
NCI NIH HHS P01 CA023766NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA055349
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adjuvants, ImmunologicAdultAgedAged, 80 and overCisplatinCombined Modality TherapyDisease-Free SurvivalDouble-Blind MethodFemaleHumansLung NeoplasmsMaleMesotheliomaMesothelioma, MalignantMiddle AgedPemetrexedAdjuvants, ImmunologicCisplatinPemetrexedVaccines, Subunit

Identifiers

PMID28972039
PMCPMC5732877
OpenAlexW2758938747

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.