Evidence map›Paper›PMID 28971860›Full record

ArticleAntimicrobial agents and chemotherapy2017

Immunohistochemical Investigations of Treatment with Ro 13-3978, Praziquantel, Oxamniquine, and Mefloquine in Schistosoma mansoni-Infected Mice.

Gordana Panic, Marie-Thérèse Ruf, Jennifer Keiser

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Development of non-sedating benzodiazepines withAntimicrobial agents and chemotherapy · 2024
    Article
  5. Article
  6. Article
  7. Development of non-sedating antischistosomal benzodiazepines.bioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis.International journal for parasitology. Drugs and drug resistance · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gordana PanicSwiss Tropical and Public Health Institute, Basel, Switzerland, and University of Basel, Basel Switzerland.
Marie-Thérèse RufSwiss Tropical and Public Health Institute, Basel, Switzerland, and University of Basel, Basel Switzerland.
Jennifer KeiserSwiss Tropical and Public Health Institute, Basel, Switzerland, and University of Basel, Basel Switzerland jennifer.keiser@swisstph.ch.
Swiss Tropical and Public Health Institute · CHUniversity of Basel · CH

Funding

Optimization of Antischistosomal ChemotypesR01AI116723 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI VENNERSTROM, JONATHAN L · 2015 to 2024
$6.2M
Increasing the Antischistosomal Selectivity of Aryl HydantoinsR21AI097802 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI VENNERSTROM, JONATHAN L · 2012 to 2013
$358k
European Research Council 614739NIAID NIH HHS R01 AI116723NIAID NIH HHS R21 AI097802
6 · The paper itself

Abstract

To date, there is only one drug in use, praziquantel, to treat more than 250 million people afflicted with schistosomiasis, a debilitating parasitic disease. The aryl hydantoin Ro 13-3978 is a promising drug candidate with

Indexed as

AnimalsB-LymphocytesFemaleHydantoinsMacrophagesMaleMefloquineMiceOxamniquinePraziquantelSchistosoma mansoniSchistosomiasis mansoniSchistosomicidesT-LymphocytesHydantoinsMefloquineOxamniquinePraziquantelRo 13-3978SchistosomicidesimmunohistochemistrymefloquineoxamniquinepraziquantelRo 13-3978Schistosoma mansoni

Identifiers

PMID28971860
PMCPMC5700362
OpenAlexW2762974290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.