Evidence map›Paper›PMID 28971183›Full record

ArticleJournal of cancer epidemiology and prevention (iMedPub)2016

Interaction between polyunsaturated fatty acids and genetic variants in relation to breast cancer incidence.

Nikhil K Khankari, Patrick T Bradshaw, Susan E Steck, Ka He, Andrew F Olshan, Jiyoung Ahn, Mary Beth Terry, Katherine D Crew, Susan L Teitelbaum, Alfred I Neugut and 2 more

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of cancer epidemiology and prevention (iMedPub), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Nikhil K KhankariDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA.
Patrick T BradshawDivision of Epidemiology, School of Public Health, University of California, Berkeley, CA, 94720, USA.
Susan E SteckDepartment of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC, 29208, USA.
Ka HeDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, IN 47405, USA.
Andrew F OlshanDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA.
Jiyoung AhnDepartment of Population Health, New York University, New York, NY 10016, USA.
Mary Beth TerryDepartment of Epidemiology, Columbia University, New York, NY, 10032, USA.
Katherine D CrewDepartment of Epidemiology, Columbia University, New York, NY, 10032, USA.
Susan L TeitelbaumDepartment of Preventive Medicine, Mount Sinai School of Medicine, New York, NY, 10029, USA.
Alfred I NeugutDepartment of Epidemiology, Columbia University, New York, NY, 10032, USA.
Regina M SantellaDepartment of Environmental Health, Columbia University, New York, NY, 10032, USA.
Marilie D GammonDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA.
Columbia University · USUniversity of North Carolina at Chapel Hill · USIcahn School of Medicine at Mount Sinai · USIndiana University Bloomington · USNew York University · USUniversity of California, Berkeley · USUniversity of South Carolina · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
BREAST CANCER AND THE ENVIRONMENT ON LONG ISLANDU01CA066572 · NCI · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI GAMMON, MARILIE D · 1995 to 2004
$1.7M
NCI NIH HHS U01 CA066572NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Higher intake of ω-3 relative to ω-6 polyunsaturated fatty acids (PUFAs) may reduce breast carcinogenesis via different metabolic pathways. The PUFA-breast cancer association remains inconclusive, thus, we hypothesized that interactions between the ratio of dietary ω-3:ω-6 intake and polymorphisms from PUFA-related metabolic pathways would help elucidate an association. Utilizing resources from the Long Island Breast Cancer Study Project, a population-based case-control study (n=1035 cases/1075 controls), we examined interactions between ω-3:ω-6 ratio and 18 polymorphisms of 15 genes. Compared to the putative lowest risk group (high ω-3:ω-6,low-risk

Indexed as

breast cancerepidemiologyfat/omega-3omega-6/fish oilsingle nucleotide polymorphisms

Identifiers

PMID28971183
PMCPMC5621474
OpenAlexW2739846509

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.