ArticleGynecologic oncology reports2017
Malignant Brenner tumor of the ovary: Review and case report.
Article in Gynecologic oncology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Risk-adapted management of early-stage malignant Brenner tumor: eight-year outcomes and contemporary evidence review-a case report.Journal of medical case reports · 2026Review
- Imaging features and differentiation between benign and malignant Brenner tumors in a multi-center cohort.Frontiers in oncology · 2026Article
- Management of a Borderline Brenner Tumor of the Ovary in a Premenopausal Woman in Northern Tanzania. A Rare Case Report and Review of the Current Literature.Clinical case reports · 2024Article
- A report of twenty cases of ovarian Brenner tumor and literature review: a case series study.BMC women's health · 2024Review
- Review
- Borderline Brenner tumor of the ovary with mucinous metaplasia: A case report.Clinical case reports · 2023Article
- Article
- Review
- Comparison of performance between O-RADS, IOTA simple rules risk assessment and ADNEX model in the discrimination of ovarian Brenner tumors.Archives of gynecology and obstetrics · 2023Article
- A Rare Case of Ruptured Malignant Ovarian Brenner Tumor.The American journal of case reports · 2023Review
- Brenner Tumor of the Ovary: A 10-Year Single Institution Experience and Comprehensive Review of the Literature.Medical sciences (Basel, Switzerland) · 2023Review
- Thoracic spinal metastasis as recurrence of borderline Brenner tumor without local recurrence: A case report.Gynecologic oncology reports · 2022Article
- Thoracic spinal metastasis as recurrence of borderline Brenner tumor without local recurrence: A case report.Gynecologic oncology reports · 2022Article
- Coexistence of malignant ovarian Brenner tumor and borderline mucinous cystadenoma, combined with primary uterine corpus endometrioid carcinoma: A case report and literature review.Oncology letters · 2022Article
- Brenner tumors of the ovary: clinical features and outcomes in a single-center cohortJournal of the Turkish German Gynecological Association · 2022Article
- A case of a vaginal Brenner tumor without a gland mimicking a borderline tumor: unusual morphology and diagnostic pitfalls.The Journal of international medical research · 2020Article
- Primary Squamous Cell Carcinoma of the Ovary.Cureus · 2019Article
- Malignant Brenner tumor of the ovary: Case series and review of treatment strategies.Gynecologic oncology reports · 2019Article
- Malignant Brenner tumor: Two case reports.Case reports in women's health · 2018Article
- Bilateral Malignant Brenner Tumor of the Ovary.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ovarian neoplasms are a heterogeneous group of tumors with varying incidence in the general population. The most common are the surface epithelial tumors which include transitional cell tumors. Transitional cell tumors include both transitional cell carcinoma and Brenner tumor. The vast majority of Brenner tumors are benign, often incidental findings; however, malignant Brenner tumors (MBT) do occasionally occur. MBT present similarly to other ovarian neoplasms with abdominal pain and bulk symptoms. On imaging, these tumors demonstrate nonspecific findings. Microscopically, they demonstrate areas of conventional benign Brenner tumor juxtaposed with regions of frank malignancy showing marked cytologic atypia and infiltration. There is no consistent tumor marker for these tumors, but CA-125, CA 72-4 and SCC have been reported in singular instances. Tumors express several immunohistochemical markers of urothelial differentiation including uroplakin III, thrombomodulin, GATA3, p63, as well as cytokeratin 7. The primary treatment modality is surgical excision. Due to their rarity, the precise role and regimen of adjuvant chemo-radiation therapy for MBT has not been established. We herein review a case of MBT with emphasis on primary treatment and treatment of recurrent disease, including the use of adjuvant pelvic radiation, discuss the current state of the literature and standards of practice regarding this malignancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.